Rickettsia canadensis str. McKiel

Gram-negativeBacilliNon-motileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Rickettsiales

Family

Rickettsiaceae

Genus

Rickettsia

Description

Rickettsia canadensis was first isolated from Haemaphysalis leporispalustris ticks removed from rabbits in Ontario, Canada. It was initially considered a member of the typhus group rickettsiae on the basis of antigenic similarities. However, according to recent molecular studies, it is thought to be a representative of a distinct group within the genus rickettsia, such as Rickettsia bellii. The role of Rickettsia canadensis as a human pathogen has not been definitively established. Serological evidence of infection has been reported in four patients presenting with an RMSF-like disease in California and Texas. A role for Rickettsia canadensis in acute cerebral vasculitis was also suspected in a patient from southwestern Ohio, based on serological studies that included immunoblot analysis. This description is based on PubMed 16223955. (EBI Integr8)

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassAlphaproteobacteria
OrderRickettsiales
FamilyRickettsiaceae
GenusRickettsia
SpeciesRickettsia canadensis
StrainMcKiel

Profile

Physiology
Gram staining propertiesNegative
ShapeBacilli
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Rickettsia canadensis str. McKiel
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Tick- Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityProbable

Genome Summary

Rickettsia canadensis str. McKiel


Gene Summary

Adenine Count

398667 bp

Thymine Count

400950 bp

Guanine Count

180128 bp

Cytosine Count

180027 bp

Genome Length

1159772 bp

Protein-coding Genes

1053 genes

Non-Coding Genes

39 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
pyruvate, water dikinase regulatory proteinA1E_RS00005Not Available+1 - 82231683.5
thioredoxinA1E_RS00010Not Available+1065 - 138212045.6
abc transporter atp-binding proteinA1E_RS00015Not Available+1393 - 213627589.8
abc transporter permeaseA1E_RS00020Not Available+2295 - 307130018.0
bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylaseA1E_RS00025Not Available+3068 - 6214120624.0
acyl-acp--udp-n-acetylglucosamine o-acyltransferaseA1E_RS00030Not Available-6333 - 712728447.3
3-hydroxyacyl-acp dehydratase fabzA1E_RS00035Not Available-7135 - 756916238.2
udp-3-o-(3-hydroxymyristoyl)glucosamine n-acyltransferaseA1E_RS00040Not Available-7570 - 859836898.8
Trna-pheNot AvailableNot Available+8620 - 8695Not Available
trna dihydrouridine synthase dusbA1E_RS00050Not Available+8865 - 984535585.1

Displaying genes 1 – 10 of 1092 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

500 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001462ubiquinone-0C9H10O4Chemical structure of ubiquinone-0605-94-7
Average182.1733Da
Monoisotopic182.057908808Da
BASm00016962-heptyl-3-hydroxy-4(1H)-quinoloneC16H21NO2Chemical structure of 2-heptyl-3-hydroxy-4(1H)-quinoloneNot available
Average259.349Da
Monoisotopic259.15722892Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00021577-cyano-7-deazaguanineC7H5N5OChemical structure of 7-cyano-7-deazaguanineNot available
Average175.1475Da
Monoisotopic175.0494098Da

Displaying 1–10 of 500 metabolites