Rickettsia typhi str. Wilmington

Gram-negativeBacilliNon-motileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Rickettsiales

Family

Rickettsiaceae

Genus

Rickettsia

Description

Rickettsia typhi is the causative agent of murine typhus or endemic typhus. Infection with Rickettsia typhi causes headache, fever, myalgia and leads to multisystem disease, including infection of the brain, lung, liver, kidney and heart. In severe cases R.typhi can cause meningoencephalitis, interstitial pneumonia and disseminated vascular lesions. It can be transmitted to the mammalian host by the bite of an infected flea or louse but the most important mechanism of inoculation is through the feces of the vector. Although distributed worldwide, it is mostly present in warm coastal areas harbouring large rat populations.(From http://www.expasy.org/sprot/hamap/RICTY.html) (BacMap)

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassAlphaproteobacteria
OrderRickettsiales
FamilyRickettsiaceae
GenusRickettsia
SpeciesRickettsia typhi
StrainWilmington

Profile

Physiology
Gram staining propertiesNegative
ShapeBacilli
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Rickettsia typhi str. Wilmington
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Rickettsia typhi str. Wilmington


Gene Summary

Adenine Count

394937 bp

Thymine Count

395121 bp

Guanine Count

158477 bp

Cytosine Count

162961 bp

Genome Length

1111496 bp

Protein-coding Genes

837 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
pyruvate, water dikinase regulatory proteinRT_RS00005Not Available+1 - 82231657.4
thioredoxinRT_RS00010Not Available+984 - 130112065.8
abc transporter atp-binding proteinRT_RS00015Not Available+1312 - 207028250.7
abc transporter permeaseRT_RS00020Not Available+2067 - 284329932.1
fad-dependent oxidoreductaseRT_RS00025Not Available+2840 - 5896116707.0
acyl-acp--udp-n-acetylglucosamine o-acyltransferaseRT_RS00030Not Available-6007 - 680128517.4
3-hydroxyacyl-acp dehydratase fabzRT_RS00035Not Available-6811 - 724816443.5
udp-3-o-(3-hydroxymyristoyl)glucosamine n-acyltransferaseRT_RS00040Not Available-7429 - 846937252.9
Trna-pheNot AvailableNot Available+8851 - 8926Not Available
trna dihydrouridine synthase dusbRT_RS00050Not Available+9295 - 1027835692.9

Displaying genes 1 – 10 of 877 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

629 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001462ubiquinone-0C9H10O4Chemical structure of ubiquinone-0605-94-7
Average182.1733Da
Monoisotopic182.057908808Da

Displaying 1–10 of 629 metabolites