Spirosoma linguale DSM 74

Gram-negativeSpirillaNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Cytophagia

Order

Cytophagales

Family

Cytophagaceae

Genus

Spirosoma

Description

Spirosoma linguale DSM 74 is a gram-negative, spiral-shaped bacterium that thrives optimally at mesophilic temperatures, is classified as a chemoheterotroph, and functions as a facultative anaerobe. This microorganism is found in a variety of environmental niches, including the human oral cavity; its presence reflects the dynamic microbial ecosystem that exists in and on human bodies.The gram-negative nature of Spirosoma linguale indicates that it has a thin peptidoglycan layer surrounded by an outer membrane containing lipopolysaccharides, which contributes to its distinctive staining characteristics and plays a vital role in its interaction with host organisms. Its spiral morphology allows for increased motility, which is advantageous for navigating through viscous environments such as mucosal surfaces. As a mesophilic organism, Spirosoma linguale exhibits growth preferences that align with moderate temperature ranges, typically between 20°C and 45°C. This temperature adaptability enables it to thrive in various habitats, aligning with the thermal conditions of the human oral cavity, which is often subject to fluctuating temperatures. Being a chemoheterotroph, Spirosoma linguale derives its energy from organic compounds, predominantly found in the microbial communities of the mouth. As a facultative anaerobe, it can grow in both the presence and absence of oxygen, allowing it to exploit diverse ecological niches and adjust its metabolic pathways depending on environmental conditions. A notable aspect of Spirosoma linguale is its potential role in oral health. Studies suggest that it may influence the balance of oral microbiota, possibly impacting conditions such as dental caries and periodontal disease. Its unique morphology and metabolic capabilities make it a subject of interest for researchers exploring microbial ecology and its implications for human health.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassCytophagia
OrderCytophagales
FamilyCytophagaceae
GenusSpirosoma
SpeciesSpirosoma linguale
StrainDSM 74

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature20
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityNo

Gene Summary

Adenine Count

2086 bp

Thymine Count

1961 bp

Guanine Count

1833 bp

Cytosine Count

1803 bp

Genome Length

7683 bp

Protein-coding Genes

9 genes

Non-Coding Genes

1 genes

# of Chromosomes/Plasmids

9

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
replication initiation proteinSLIN_RS34420Not Available+668 - 164237708.6
brnt family toxinSLIN_RS34425Not Available+1635 - 195512240.3
hypothetical proteinSLIN_RS34430Not Available-2098 - 271822895.3
relaxase/mobilization nuclease domain-containing proteinSLIN_RS34435Not Available-2720 - 360433404.8
plasmid mobilization proteinSLIN_RS34440Not Available-3601 - 395712840.5
outer membrane beta-barrel proteinSLIN_RS34445Not Available+4191 - 482322820.2
hypothetical proteinSLIN_RS34450Not Available-4830 - 515011986.2
phosphatase pap2 family proteinSLIN_RS34455Not Available-5741 - 660431685.5
terb family tellurite resistance proteinSLIN_RS34460Not Available+6954 - 771526683.0
hypothetical proteinSLIN_RS34465Not Available+7816 - 80679253.36

Displaying genes 1 – 10 of 6884 in total

Metabolites

30 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00019783-(4-hydroxyphenyl)pyruvateC9H7O4Chemical structure of 3-(4-hydroxyphenyl)pyruvateNot available
Average179.1495Da
Monoisotopic179.034433712Da
BASm0002131(3S)-hydroxy-3-methylglutaryl-CoAC27H39N7O20P3SChemical structure of (3S)-hydroxy-3-methylglutaryl-CoANot available
Average906.62Da
Monoisotopic906.1183419Da
BASm00021577-cyano-7-deazaguanineC7H5N5OChemical structure of 7-cyano-7-deazaguanineNot available
Average175.1475Da
Monoisotopic175.0494098Da
BASm0002529(3S)-3-hydroxy-L-aspartateC4H6NO5Chemical structure of (3S)-3-hydroxy-L-aspartateNot available
Average148.095Da
Monoisotopic148.0251459Da
BASm00031233',5'-cyclic CMPC9H11N3O7PNot availableNot available
Average304.175Da
Monoisotopic304.034010284Da
BASm0003308N(2)-succinyl-L-arginineC10H17N4O5Chemical structure of N(2)-succinyl-L-arginineNot available
Average273.27Da
Monoisotopic273.120443243Da
BASm0003333(2R)-3-phosphoglycerateC3H4O7PChemical structure of (2R)-3-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da

Displaying 1–10 of 30 metabolites