Spirosoma linguale DSM 74

Gram-negativeSpirillaNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Cytophagia

Order

Cytophagales

Family

Cytophagaceae

Genus

Spirosoma

Description

Spirosoma linguale DSM 74 is a gram-negative, spiral-shaped bacterium that thrives optimally at mesophilic temperatures, is classified as a chemoheterotroph, and functions as a facultative anaerobe. This microorganism is found in a variety of environmental niches, including the human oral cavity; its presence reflects the dynamic microbial ecosystem that exists in and on human bodies.The gram-negative nature of Spirosoma linguale indicates that it has a thin peptidoglycan layer surrounded by an outer membrane containing lipopolysaccharides, which contributes to its distinctive staining characteristics and plays a vital role in its interaction with host organisms. Its spiral morphology allows for increased motility, which is advantageous for navigating through viscous environments such as mucosal surfaces. As a mesophilic organism, Spirosoma linguale exhibits growth preferences that align with moderate temperature ranges, typically between 20°C and 45°C. This temperature adaptability enables it to thrive in various habitats, aligning with the thermal conditions of the human oral cavity, which is often subject to fluctuating temperatures. Being a chemoheterotroph, Spirosoma linguale derives its energy from organic compounds, predominantly found in the microbial communities of the mouth. As a facultative anaerobe, it can grow in both the presence and absence of oxygen, allowing it to exploit diverse ecological niches and adjust its metabolic pathways depending on environmental conditions. A notable aspect of Spirosoma linguale is its potential role in oral health. Studies suggest that it may influence the balance of oral microbiota, possibly impacting conditions such as dental caries and periodontal disease. Its unique morphology and metabolic capabilities make it a subject of interest for researchers exploring microbial ecology and its implications for human health.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassCytophagia
OrderCytophagales
FamilyCytophagaceae
GenusSpirosoma
SpeciesSpirosoma linguale
StrainDSM 74

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature20
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityNo

Gene Summary

Adenine Count

2498 bp

Thymine Count

2325 bp

Guanine Count

1897 bp

Cytosine Count

1931 bp

Genome Length

8651 bp

Protein-coding Genes

11 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

9

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
replication initiation proteinSLIN_RS34420Not Available+668 - 164237708.6
brnt family toxinSLIN_RS34425Not Available+1635 - 195512240.3
hypothetical proteinSLIN_RS34430Not Available-2098 - 271822895.3
relaxase/mobilization nuclease domain-containing proteinSLIN_RS34435Not Available-2720 - 360433404.8
plasmid mobilization proteinSLIN_RS34440Not Available-3601 - 395712840.5
outer membrane beta-barrel proteinSLIN_RS34445Not Available+4191 - 482322820.2
hypothetical proteinSLIN_RS34450Not Available-4830 - 515011986.2
phosphatase pap2 family proteinSLIN_RS34455Not Available-5741 - 660431685.5
terb family tellurite resistance proteinSLIN_RS34460Not Available+6954 - 771526683.0
hypothetical proteinSLIN_RS34465Not Available+7816 - 80679253.36

Displaying genes 1 – 10 of 6884 in total

Metabolites

7 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00029834-CDP-2-C-methyl-D-erythritolC14H23N3O14P2Chemical structure of 4-CDP-2-C-methyl-D-erythritolNot available
Average519.294Da
Monoisotopic519.0666236Da
BASm00030584-CDP-2-C-methyl-D-erythritol 2-phosphateC14H22N3O17P3Chemical structure of 4-CDP-2-C-methyl-D-erythritol 2-phosphateNot available
Average597.257Da
Monoisotopic597.0184016Da
BASm0003335L-glutamyl 5-phosphateC5H8NO7PChemical structure of L-glutamyl 5-phosphateNot available
Average225.094Da
Monoisotopic225.0049358Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0003969(2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerateC9H14O12PChemical structure of (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerateNot available
Average345.174Da
Monoisotopic345.023933629Da
BASm0012597(6R)-10-formyltetrahydrofolateC20H21N7O7Chemical structure of (6R)-10-formyltetrahydrofolateNot available
Average471.431Da
Monoisotopic471.151343204Da

Displaying 1–7 of 7 metabolites