Fusobacterium nucleatum strain 12230

Gram-negativeRodNon-motileAnaerobe

Kingdom

Fusobacteriati

Phylum

Fusobacteriota

Class

Fusobacteriia

Order

Fusobacteriales

Family

Fusobacteriaceae

Genus

Fusobacterium

Description

Fusobacterium nucleatum strain 12230 is a Gram-negative, rod-shaped bacterium that thrives as a nonsporulating anaerobe, with an optimal growth temperature of 37.0 °C. This strain is predominantly host-associated, indicating a symbiotic or commensal relationship with its host organisms. Fusobacterium nucleatum is known for its role in the human oral cavity, where it is part of the normal microbiota, although it can also be implicated in various oral diseases. The anaerobic nature of this bacterium suggests that it occupies niches within the host that are low in oxygen, such as periodontal pockets or other anaerobic environments within the body. The ability of F. nucleatum to establish itself in these anaerobic habitats may be critical for its survival and potential interactions with other microbial communities. Its presence in these specific environments highlights the intricate relationships within the microbiome and the potential for interspecies interactions, which can influence both health and disease states in the host. Understanding the ecological role of F. nucleatum strain 12230 could provide insights into its contribution to the stability and function of microbial communities in host-associated environments.

Taxonomy

KingdomFusobacteriati
PhylumFusobacteriota
ClassFusobacteriia
OrderFusobacteriales
FamilyFusobacteriaceae
GenusFusobacterium
SpeciesFusobacterium nucleatum
Strainstrain 12230

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Fusobacterium nucleatum strain 12230
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Oryctolagus cuniculus
Cell arrangementPairs
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityAnimal

Genome Summary

Fusobacterium nucleatum strain 12230


Gene Summary

Adenine Count

862641 bp

Thymine Count

915782 bp

Guanine Count

306876 bp

Cytosine Count

344203 bp

Genome Length

2429502 bp

Protein-coding Genes

2297 genes

Non-Coding Genes

102 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Predicted holinDNF10_00865Not AvailableNegative183667 - 18407115140.4
hypothetical proteinDNF10_00870Not AvailableNegative184084 - 1843269311.89
hypothetical proteinDNF10_00875Not AvailableNegative184323 - 18468814023.4
N-acetylmuramoyl-l-alanine amidaseDNF10_00880Not AvailableNegative184699 - 18531023812.6
penicillin-binding proteinDNF10_00885Not AvailableNegative185307 - 18605630055.1
AttlNot AvailableNot AvailablePositive186066 - 186077Not Available
Recombinase/integraseDNF10_00890Not AvailableNegative186247 - 18722138686.1
hypotheticalDNF10_00895Not AvailablePositive187249 - 18759312620.3
hypothetical proteinDNF10_00900Not AvailableNegative187590 - 18786510135.1
Tail proteinDNF10_00905Not AvailableNegative188443 - 18917727884.9

Displaying genes 1 – 10 of 2399 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Lemierre s syndromeCausesPMC9009667
Colorectal cancerCausesPMC10394142
Gingival diseasesCausesPMC9318310
Dental infectionsCausesPMC9318310
Colorectal cancerCausesPMC11767858
CarcinogenicCausesPMC11792494
Chronic oral and intestinal diseasesCausesPMC8604900

Displaying health effects 1 – 7 of 7 in total