Helicobacter pylori strain HP42K

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain HP42K is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with its adaptation to a host-associated habitat, typically found in the gastric mucosa of mammals. The microaerophilic nature of H. pylori strain HP42K indicates that it requires reduced oxygen levels for growth, which is consistent with its ecological niche within the host stomach, where oxygen concentrations are lower than in the atmosphere. This bacterium's unique morphology, combined with its specific habitat and growth requirements, highlights its specialized adaptations for survival in a challenging environment. The strain's association with the gastric environment suggests potential roles in influencing local microbial communities, possibly affecting host health and disease states. Understanding the ecological dynamics of H. pylori strain HP42K may provide insights into its interactions with both the host and other microbial inhabitants of the gastric ecosystem, revealing the intricate balance maintained within this specialized habitat.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain HP42K

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain HP42K
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain HP42K


Gene Summary

Adenine Count

3334 bp

Thymine Count

3068 bp

Guanine Count

1789 bp

Cytosine Count

1822 bp

Genome Length

10013 bp

Protein-coding Genes

14 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
replication initiation proteinD8X56_RS00005Not AvailablePositive1 - 126349503.1
transcription antitermination factor nusbD8X56_RS00080Not AvailableNegative1 - 41715491.9
6,7-dimethyl-8-ribityllumazine synthaseD8X56_RS00085Not AvailableNegative419 - 88916953.7
3-deoxy-8-phosphooctulonate synthaseD8X56_RS00090Not AvailableNegative899 - 172930295.5
carbonic anhydraseD8X56_RS00095Not AvailableNegative1716 - 238125796.9
orotidine-5'-phosphate decarboxylaseD8X56_RS00100Not AvailablePositive2503 - 318625346.1
pantoate--beta-alanine ligaseD8X56_RS00105Not AvailablePositive3187 - 401731107.9
Trna-gluNot AvailableNot AvailablePositive4031 - 4106Not Available
Trna-aspNot AvailableNot AvailablePositive4170 - 4246Not Available
Trna-valNot AvailableNot AvailablePositive4287 - 4362Not Available

Displaying genes 1 – 10 of 1588 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 66 in total