Helicobacter pylori strain 26695-dR

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 26695-dR is a Gram-negative, microaerophilic bacterium characterized by its spiral shape and single-cell arrangement. It thrives optimally at a temperature of 37.0°C, which aligns with the physiological conditions found in human hosts, indicating its adaptation to a host-associated habitat. This strain is notable for its unique morphological features, which contribute to its ability to colonize the gastric mucosa of the host. The microaerophilic nature of H. pylori suggests that it requires reduced levels of oxygen for growth, reflecting its specialized ecological niche within the gastric environment. In addition to its morphological and physiological traits, the ability of H. pylori strain 26695-dR to survive in the acidic conditions of the stomach underscores the evolutionary adaptations that enable this microbe to persist in such a challenging habitat. Understanding the traits of this strain not only enhances our knowledge of H. pylori biology but also informs potential avenues for research into its interactions with the host microbiome and implications for gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 26695-dR

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 26695-dR
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 26695-dR


Gene Summary

Adenine Count

505352 bp

Thymine Count

513178 bp

Guanine Count

321031 bp

Cytosine Count

326910 bp

Genome Length

1666471 bp

Protein-coding Genes

1558 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcription antitermination factor nusbC2840_RS00005Not AvailableNegative154 - 57015522.0
6,7-dimethyl-8-ribityllumazine synthaseC2840_RS00010Not AvailableNegative572 - 104217043.7
3-deoxy-8-phosphooctulonate synthaseC2840_RS00015Not AvailableNegative1052 - 188230347.7
carbonic anhydraseC2840_RS00020Not AvailableNegative1869 - 253425516.4
orotidine-5'-phosphate decarboxylaseC2840_RS00025Not AvailablePositive2656 - 333925385.1
pantoate--beta-alanine ligaseC2840_RS00030Not AvailablePositive3340 - 417031207.2
Trna-gluNot AvailableNot AvailablePositive4184 - 4259Not Available
Trna-aspNot AvailableNot AvailablePositive4322 - 4398Not Available
Trna-valNot AvailableNot AvailablePositive4439 - 4514Not Available
Trna-gluNot AvailableNot AvailablePositive4556 - 4630Not Available

Displaying genes 1 – 10 of 1603 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 66 in total