Helicobacter pylori strain 7.13_D1b

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 7.13_D1b is a Gram-negative, microaerophilic bacterium characterized by its distinct spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, indicating its adaptation to a warm-blooded host environment. As a member of the Helicobacter genus, strain 7.13_D1b is typically found associated with the gastric mucosa of hosts, where it may play a role in complex host-microbe interactions. The microaerophilic nature of H. pylori strain 7.13_D1b suggests that it requires reduced levels of oxygen for growth, which aligns with its ecological niche in the gastric environment, where oxygen levels are lower than in the atmosphere. The spiral morphology of this bacterium may facilitate its motility within the viscous gastric mucus, potentially enabling it to colonize and persist in this unique habitat. Further investigation of H. pylori strain 7.13_D1b could provide insights into its metabolic capabilities and interactions within the host, particularly how it adapts to the fluctuating conditions of the gastric environment. Understanding the physiological traits of this strain may also contribute valuable information regarding the ecological dynamics of Helicobacter species in host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 7.13_D1b

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 7.13_D1b
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 7.13_D1b


Gene Summary

Adenine Count

515865 bp

Thymine Count

508757 bp

Guanine Count

328006 bp

Cytosine Count

321414 bp

Genome Length

1674080 bp

Protein-coding Genes

1537 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
chromosomal replication initiator protein dnaaBXP09_RS00010Not AvailablePositive154 - 152751687.1
hypothetical proteinBXP09_RS00015Not AvailablePositive1756 - 319554760.4
Trna-pheNot AvailableNot AvailablePositive3198 - 3273Not Available
exodeoxyribonuclease iiiBXP09_RS00025Not AvailablePositive3376 - 412829223.8
outer membrane proteinBXP09_RS00030Not AvailableNegative4125 - 476024826.9
hypothetical proteinBXP09_RS00035Not AvailableNegative4764 - 511113289.3
atp-dependent dna helicase recgBXP09_RS00040Not AvailablePositive5193 - 706471412.1
restriction endonuclease subunit sBXP09_RS00045Not AvailablePositive7107 - 915975966.5
type iii restriction-modification system endonucleaseBXP09_RS00050Not AvailablePositive9162 - 12071111668.0
restriction endonuclease subunit sBXP09_RS00055Not AvailablePositive12178 - 16076150628.0

Displaying genes 1 – 10 of 1582 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 66 in total