Faecalibacterium prausnitzii strain CNCM I 4575

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Oscillospiraceae

Genus

Faecalibacterium

Description

Faecalibacterium prausnitzii strain CNCM I 4575 is a Gram-positive, nonsporulating rod-shaped bacterium that functions as a chemoheterotroph and thrives optimally at a temperature of 37.0°C. This strain is strictly anaerobic, indicating that it does not require oxygen for growth and may even be inhibited by its presence. F. prausnitzii is known to inhabit various environments, with its predominant habitat being the human gastrointestinal tract, where it plays a significant role in maintaining gut health. As an anaerobe, it contributes to the complex microbial ecosystem within the gut, participating in fermentation processes and producing short-chain fatty acids that are beneficial for intestinal health. The presence of F. prausnitzii is often associated with a balanced gut microbiota, and its levels may fluctuate in response to changes in diet or health status. This strain may be particularly important in the context of gut dysbiosis, as it is thought to exert anti-inflammatory effects. The unique ecological insight about F. prausnitzii strain CNCM I 4575 lies in its potential role as a keystone species in the gut microbiome; its abundance may be critical for maintaining the stability and functionality of the microbial community, thereby influencing overall host health and disease resistance.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyOscillospiraceae
GenusFaecalibacterium
SpeciesFaecalibacterium prausnitzii
Strainstrain CNCM I 4575

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Faecalibacterium prausnitzii strain CNCM I 4575
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Faecalibacterium prausnitzii strain CNCM I 4575


Gene Summary

Adenine Count

638413 bp

Thymine Count

638598 bp

Guanine Count

865384 bp

Cytosine Count

863857 bp

Genome Length

3006602 bp

Protein-coding Genes

2670 genes

Non-Coding Genes

165 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Dna polymeraseCGS58_06730Not Available-1426948 - 142751421307.7
phosphate acetyltransferaseCGS58_06735Not Available+1427702 - 142872735748.2
Putative dna polymerase iiiCGS58_06745Not Available+1429197 - 143107767833.7
nucleoid-associated protein, ybab/ebfc familyCGS58_06750Not Available+1431098 - 143143611993.5
recombination protein recrCGS58_06755Not Available+1431456 - 143205521774.4
Ssra-binding proteinCGS58_06760Not Available+1432166 - 143264818280.2
Tmrna,resume;Not AvailableNot Available+1432714 - 1433062Not Available
Hypothetical proteinCGS58_06770Not Available+1433304 - 143364212750.8
Hypothetical proteinCGS58_06775Not Available+1433790 - 14340058052.54
Hypothetical proteinCGS58_06780Not Available+1434019 - 143432711853.1

Displaying genes 1 – 10 of 2835 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da

Displaying 1–10 of 135 metabolites