Faecalibacterium prausnitzii L2-6

RodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Oscillospiraceae

Genus

Faecalibacterium

Description

Faecalibacterium prausnitzii L2-6 is a bacterium that thrives in a mesophilic environment, with a temperature preference category of 20-45°C. It belongs to the group of heterotrophs, which means it requires an external source of energy, obtained through the breakdown of organic compounds. Specifically, this microbe is a chemoheterotroph, utilizing energy from the oxidation of organic molecules. In terms of energy production, F. prausnitzii L2-6 likely employs anaerobic respiration, generating ATP through the fermentation of carbohydrates. This is consistent with its ability to grow well in the absence of oxygen. The bacterium stains Gram-positive, indicating the presence of a thick peptidoglycan layer in its cell wall. Its shape is typically rod-shaped, with a length of approximately 2-4 μm. F. prausnitzii L2-6 is a strict anaerobe, preferring to grow in environments with low or no oxygen levels. It is unable to survive in aerobic environments and is sensitive to oxygen. As a commensal microbe, F. prausnitzii L2-6 is commonly found in the gastrointestinal tracts of humans and other mammals, where it plays a crucial role in maintaining gut health. It is one of the most abundant species in the human gut microbiome, contributing to the production of short-chain fatty acids and the modulation of the immune response. Notably, F. prausnitzii L2-6 has been linked to various physiological and pathological processes, including the development of obesity, type 2 diabetes, and inflammatory bowel disease. Its dysbiosis has been associated with impaired gut function and increased susceptibility to infections. Research on this microbe has significant implications for the development of novel therapies and diagnostic approaches for gastrointestinal disorders.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyOscillospiraceae
GenusFaecalibacterium
SpeciesFaecalibacterium prausnitzii
StrainNo strain

Profile

Physiology
Gram staining propertiesStructurally positive but stains negative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Faecalibacterium prausnitzii L2-6

Accession NumberNC_021042.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

3054 genes

Non-Coding Genes

238 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+16734 - 16747Not Available
Phage integrase family prophage lambdach01FP2_RS00200Not Available+30658 - 3204952687.1
abrb/maze/spovt family dna-binding domain-containing proteinFP2_RS00205Not Available+33095 - 3349915471.5
dna topoisomerase 3FP2_RS00210Not Available-33903 - 3582871388.3
duf4366 domain-containing proteinFP2_RS00215Not Available-35889 - 3662626418.4
duf4315 family proteinFP2_RS00220Not Available-36610 - 368799956.63
PeptidaseFP2_RS00225Not Available-36892 - 3864965182.6
virb4-like conjugal transfer atpaseFP2_RS00230Not Available-38642 - 3919921294.5
Tail tape measure proteinFP2_RS16305Not Available-39147 - 3990526234.7
Hypothetical proteinFP2_RS16580Not Available-40370 - 404985069.09

Displaying genes 1 – 10 of 33 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

292 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da

Displaying 1–10 of 292 metabolites