Helicobacter pylori strain UM196

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain UM196 is a Gram-negative, microaerophilic bacterium characterized by its spiral-shaped morphology and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, indicating its adaptation to the physiological conditions of its host environment. As a member of the Helicobacter genus, H. pylori strain UM196 is typically associated with the gastrointestinal tract of its hosts, where it can establish a niche within the mucosal lining. The microaerophilic nature of this bacterium suggests that it requires reduced oxygen levels for growth, which aligns with its ecological adaptation to the stomach's unique environment, where oxygen availability is limited. The host-associated habitat of H. pylori strain UM196 underscores its potential role in the complex microbial communities of the gastrointestinal system, where it may contribute to various host-microbiome interactions. The specific traits of this strain could provide insights into its ecological dynamics, including its potential interactions with other microbial species and its influence on host health and disease. Understanding the precise ecological role of H. pylori strain UM196 within its habitat may further illuminate the intricate relationships that exist within the gastric microbiome.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain UM196

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain UM196
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain UM196


Gene Summary

Adenine Count

497738 bp

Thymine Count

505044 bp

Guanine Count

308406 bp

Cytosine Count

322103 bp

Genome Length

1633389 bp

Protein-coding Genes

1479 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+96 - 213Not Available
restriction endonuclease subunit rACM32_00005Q58611+289 - 257188749.1
n-6 dna methylaseACM32_00010Not Available+2561 - 419262216.1
restriction endonuclease subunit sACM32_00015Not Available+4185 - 522539833.3
Trna-proNot AvailableNot Available+5291 - 5368Not Available
polyphosphate kinaseACM32_00025O25654+5462 - 748977941.8
diguanylate cyclaseACM32_00030B2USR9+7526 - 858139011.5
proteaseACM32_00035O25656+8578 - 991250286.6
4-hydroxy-tetrahydrodipicolinate synthaseACM32_00040B6JL09+9927 - 1082933300.5
7-alpha-hydroxysteroid dehydrogenaseACM32_00045P71079+10826 - 1161428600.2

Displaying genes 1 – 10 of 1521 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites