Helicobacter pylori strain UM119

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain UM119 is a Gram-negative bacterium characterized by its spirilla morphology and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, indicating its adaptation to the human body, where it is typically found in association with host tissues. H. pylori strain UM119 exhibits a microaerophilic oxygen requirement, suggesting that it flourishes in environments with reduced oxygen levels, which is consistent with its colonization of the gastric mucosa. As a member of the Helicobacter genus, strain UM119 likely plays a role in the complex interactions within the host's gastrointestinal tract. Its microaerophilic nature may enable it to exploit the unique biochemical niches present in the stomach, where oxygen levels are lower than in the surrounding environment. This adaptation not only aids in its survival but may also influence the composition of the microbial community within the gastric ecosystem. Understanding the physiological traits of H. pylori strain UM119 can provide insights into its ecological role and potential interactions with both host and other microbial species in the gastric environment.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain UM119

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain UM119
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain UM119


Gene Summary

Adenine Count

488433 bp

Thymine Count

486326 bp

Guanine Count

305015 bp

Cytosine Count

312114 bp

Genome Length

1592071 bp

Protein-coding Genes

1457 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+98 - 215Not Available
hypothetical proteinAC783_00005Not Available-340 - 70213514.4
initiator repb proteinAC783_00015Not Available-1896 - 319150424.2
hypothetical proteinAC783_00020Not Available-3824 - 410510334.5
phosphoesteraseAC783_00030O25683+6137 - 718040182.6
chemotaxis protein cheyAC783_00035O06978-7511 - 818225466.6
metallophosphoesteraseAC783_00040O25685-8531 - 964342271.8
acetyl-coa synthetaseAC783_00045Q1CUA3+9841 - 1182975053.4
ribosome maturation protein rimpAC783_00050B2USN6-11937 - 1237716643.1
ribosome-binding factor aAC783_00055B2USN5-12370 - 1270512551.2

Displaying genes 1 – 10 of 1499 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 94 metabolites