Cutibacterium acnes JCM 18920

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes JCM 18920 is a Gram-positive, non-sporulating rod-shaped bacterium that thrives in anaerobic conditions and is typically associated with host environments. This microbe has an optimal growth temperature of 37.0°C, which aligns with the physiological conditions found in mammalian hosts, suggesting its adaptation to life on human skin and within hair follicles. C. acnes is a member of the skin microbiota, where it plays a critical role in maintaining the balance of microbial communities. Although often studied in the context of skin health, its exact contributions to host homeostasis remain an area of active research. The anaerobic nature of this bacterium indicates its reliance on environments devoid of oxygen, which is characteristic of deeper skin layers and hair follicles, where it can thrive without competition from aerobic organisms. Furthermore, the ability of C. acnes to survive and proliferate in such niches may be linked to its metabolic pathways, which are adapted to utilize skin-derived nutrients. This unique ecological position not only highlights its role in skin microbiome dynamics but also emphasizes the importance of maintaining microbial diversity for skin health. Understanding the specific functions and interactions of C. acnes within its habitat could provide insights into potential therapeutic approaches for skin-related conditions, emphasizing the delicate interplay between host and microbial communities.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
StrainJCM 18920

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes JCM 18920
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes JCM 18920


Gene Summary

Adenine Count

478706 bp

Thymine Count

511968 bp

Guanine Count

770073 bp

Cytosine Count

716145 bp

Genome Length

2476892 bp

Protein-coding Genes

3343 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Trna-5s rnaNot AvailableNot Available+254 - 374Not Available
Large subunit ribosomal rnaNot AvailableNot Available+477 - 3559Not Available
acetyltransferaseJCM18920_1Not Available-8 - 49016980.6
membrane spanning proteinJCM18920_2Not Available+626 - 105715775.6
oligopeptide transporterJCM18920_3Not Available+1132 - 311968074.6
Small subunit ribosomal rnaNot AvailableNot Available+3776 - 5293Not Available
possible oxidoreductase of the aldo/keto reductase familyJCM18920_5Not Available-3162 - 377922589.8
peptide methionine sulfoxide reductase msraJCM18920_7Not Available-4140 - 455915019.5
peptide methionine sulfoxide reductase msraJCM18920_8Not Available-4560 - 47155781.99
sodium-dependent transporterJCM18920_9Not Available+4854 - 635053683.6

Displaying genes 1 – 10 of 3392 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites