Akkermansia muciniphila CAG:154

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila CAG:154 is a Gram-negative, anaerobic coccus that typically exists in pairs or as single cells. This microbe thrives at an optimal temperature of 37.0°C, which suggests its adaptation to host-associated environments, likely within the human gastrointestinal tract. As an anaerobe, Akkermansia muciniphila CAG:154 does not require oxygen for growth, highlighting its role in the anaerobic niches of the gut microbiome. The presence of Akkermansia muciniphila in the gut is linked to mucin metabolism, where it utilizes mucin as a primary carbon source. This capacity may contribute to maintaining gut health by supporting the integrity of the mucosal barrier and modulating host immune responses. The ecological role of Akkermansia muciniphila CAG:154 in the gut underscores its potential significance in symbiotic relationships within the microbiome, particularly in balancing gut homeostasis and possibly influencing the host's metabolic processes.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila CAG:154
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila CAG:154


Gene Summary

Adenine Count

611310 bp

Thymine Count

598676 bp

Guanine Count

750010 bp

Cytosine Count

757335 bp

Genome Length

2717442 bp

Protein-coding Genes

2376 genes

Non-Coding Genes

47 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
unknownBN502_00001Not Available-422 - 75413109.8
potassium-transporting atpase a chain 2BN502_00002Not Available+1944 - 365062335.0
potassium-transporting atpase b chain 2BN502_00003Not Available+3735 - 576872539.9
potassium-transporting atpase c chain 2BN502_00004Not Available+5788 - 637221056.4
osmosensitive k channel his kinase sensorBN502_00005Not Available+6553 - 768042788.4
putative uncharacterized proteinBN502_00006Not Available+8033 - 901936494.0
putative uncharacterized proteinBN502_00007Not Available+9178 - 93907394.49
beta-lactamase domain proteinBN502_00008Not Available+9556 - 1039530281.8
rna polymerase sigma-24 subunit ecf subfamilyBN502_00009Not Available+10421 - 1101722690.5
serine/threonine protein kinaseBN502_00010Not Available+11014 - 1331786141.9

Displaying genes 1 – 10 of 2423 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–1 of 1 metabolites