Helicobacter pylori Puno120

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Puno120 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and singular cell arrangement. This organism thrives optimally at 37.0°C, indicating a preference for the warm conditions typically found in the human stomach, its primary habitat. H. pylori is known for its association with host environments, where it can inhabit gastric mucosa. As a microaerophilic species, H. pylori Puno120 requires reduced levels of oxygen for growth, which aligns with its specialized adaptation to the gastric niche, where oxygen levels are lower than in the atmosphere. The distinct morphology of this bacterium, coupled with its ability to survive in the acidic environment of the stomach, suggests a well-evolved strategy for colonization and persistence in its host. An intriguing aspect of H. pylori Puno120 is its potential role in influencing the gastric microbiome and, by extension, host health. Given its adaptation to the microaerophilic environment of the stomach, the strain may interact with other microbial communities present in the gastrointestinal tract, contributing to the complex dynamics of microbial colonization and host-microbe interactions. Further studies may elucidate the specific ecological niches occupied by H. pylori Puno120 and its impact on gastric health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainPuno120

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Puno120
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Puno120


Gene Summary

Adenine Count

491407 bp

Thymine Count

500978 bp

Guanine Count

313082 bp

Cytosine Count

319512 bp

Genome Length

1624979 bp

Protein-coding Genes

1505 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
replication initiation proteinHPPN120_RS07750Not AvailablePositive307 - 157849576.0
hypothetical proteinHPPN120_RS08205Not AvailableNegative1655 - 18256317.79
relaxase/mobilization nuclease domain-containing proteinHPPN120_RS07760P07047Negative2131 - 414678943.5
plasmid mobilization proteinHPPN120_RS07765Not AvailableNegative4136 - 448013182.0
hypothetical proteinHPPN120_RS07770Not AvailablePositive4680 - 496110871.0
type ii toxin-antitoxin system yafq family toxinHPPN120_RS07775Not AvailablePositive4970 - 523910477.0
hypothetical proteinHPPN120_RS08325Not AvailablePositive5538 - 56845072.97
replication initiation proteinHPPN120_RS07780Q8GN33Positive6298 - 783960744.3
fic family proteinHPPN120_RS07785Q23544Positive7884 - 861828075.0
fic family proteinHPPN120_RS07790Not AvailablePositive8675 - 938227524.1

Displaying genes 1 – 10 of 1562 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 94 metabolites

Health Effects

No health effects information available for this bacterium.