Helicobacter pylori Hp P-11b

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp P-11b is a Gram-negative bacterium characterized by its spirilla shape and arrangement as single cells. This microbe thrives under microaerophilic conditions, indicating its requirement for reduced oxygen levels, typically found in specific niches within host environments. Optimal growth occurs at a temperature of 37°C, which aligns with the physiological conditions of its host organisms. As a member of the Helicobacter genus, Hp P-11b is predominantly associated with the gastric mucosa of various hosts, suggesting a specialized adaptation to this environment. Its microaerophilic nature may provide competitive advantages in the complex microbial ecosystems of the gastrointestinal tract, where oxygen concentrations are limited. The unique feature of Hp P-11b being host-associated emphasizes its potential role in the dynamics of host-microbe interactions, potentially influencing host health and disease states. Further investigation into its specific ecological functions and interactions within the host could shed light on the broader implications of Helicobacter species in maintaining gastric homeostasis or contributing to gastrointestinal pathologies. Understanding such interactions is essential for elucidating the complex relationships between host organisms and their resident microbial communities.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp P-11b

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp P-11b
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp P-11b


Gene Summary

Adenine Count

514062 bp

Thymine Count

518714 bp

Guanine Count

330074 bp

Cytosine Count

332405 bp

Genome Length

1695255 bp

Protein-coding Genes

1678 genes

Non-Coding Genes

66 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+277842 - 277854Not Available
Putative transcriptional regulator proteinHPHPP11B_0291Not Available-282000 - 28283331512.7
Hypothetical proteinHPHPP11B_0292I7H0I4-282833 - 28367231360.4
Hypothetical proteinHPHPP11B_0293Not Available-283689 - 28457033422.5
Hypothetical proteinHPHPP11B_0294Not Available-284628 - 28495412755.9
Hypothetical proteinHPHPP11B_0295Not Available-284954 - 28552021666.7
Hypothetical proteinHPHPP11B_0296Not Available-285522 - 28631929530.2
Hypothetical proteinHPHPP11B_0297Not Available-286321 - 28686620936.0
Hypothetical proteinHPHPP11B_0298Not Available-286914 - 2871328327.4
Hypothetical proteinHPHPP11B_0299Not Available-287129 - 28812137688.5

Displaying genes 1 – 10 of 1744 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 94 metabolites