Campylobacter concisus 13826

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter concisus 13826 is a gram-negative, curved bacillus that thrives optimally at moderate temperatures, classifying it as a mesophile. This microbe is a chemoheterotroph, relying on organic compounds for energy and carbon, and exhibits microaerophilic behavior, meaning it requires lower levels of oxygen than what is present in the atmosphere for optimal growth. Campylobacter concisus is primarily associated with the human gastrointestinal tract, where it can be found in the oral cavity and intestines, but has also been identified in other body sites, including the respiratory tract and genitourinary system. The gram-negative nature of Campylobacter concisus is indicative of its double membrane structure, featuring an outer membrane composed of lipopolysaccharides, which can help evade the host immune response. Its curved bacillus shape enhances motility, allowing this microorganism to navigate through viscous environments like intestinal mucus. As a mesophile, it thrives at temperatures around 37°C, typical of the human body, which supports its role as a pathogen. The chemoheterotrophic lifestyle of Campylobacter concisus relies on carbohydrates and amino acids for energy, underscoring its adaptability to the nutrient-rich environments of the human gut. Its microaerophilic requirement highlights its unique metabolic adaptations, allowing it to flourish in low-oxygen environments while potentially competing with other gut flora. Campylobacter concisus has garnered attention for its association with gastrointestinal diseases, particularly inflammatory bowel disease. Emerging research suggests that dysbiosis involving this microbe may play a role in gut health and disease progression, paving the way for further studies into its pathogenic mechanisms and potential therapeutic targets. Its ability to persist in various human body sites and adapt to different environments underscores its significance in microbial ecology and human health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter concisus
Strain13826

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Campylobacter concisus 13826


Gene Summary

Adenine Count

5880 bp

Thymine Count

5071 bp

Guanine Count

2844 bp

Cytosine Count

2662 bp

Genome Length

16457 bp

Protein-coding Genes

23 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
replication initiation proteinCCC13826_RS10450Not Available+349 - 130837856.6
hypothetical proteinCCC13826_RS10455Not Available+1408 - 182715024.2
cj0814 family flagellar-dependent secreted proteinCCC13826_RS10460Not Available+1881 - 302343359.2
spore coat protein cothCCC13826_RS10465Not Available+3134 - 369720704.3
hypothetical proteinCCC13826_RS10470Not Available+3697 - 398411042.2
hypothetical proteinCCC13826_RS10475Not Available+4010 - 456720148.0
cj0814 family flagellar-dependent secreted proteinCCC13826_RS10480Not Available+4621 - 582045022.0
hypothetical proteinCCC13826_RS10485Not Available+6048 - 62788323.6
hypothetical proteinCCC13826_RS10490Not Available+6281 - 672716951.2
hypothetical proteinCCC13826_RS10495Not Available-6752 - 69708499.0

Displaying genes 1 – 10 of 2133 in total

Metabolites

1589 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da
BASm0001462ubiquinone-0C9H10O4Chemical structure of ubiquinone-0605-94-7
Average182.1733Da
Monoisotopic182.057908808Da
BASm00016962-heptyl-3-hydroxy-4(1H)-quinoloneC16H21NO2Chemical structure of 2-heptyl-3-hydroxy-4(1H)-quinoloneNot available
Average259.349Da
Monoisotopic259.15722892Da
BASm0001785(2R,3R)-tartrateC4H6O6Chemical structure of (2R,3R)-tartrate87-69-4
Average150.0868Da
Monoisotopic150.0164379Da
BASm0001808corynebactinC39H42N6O18Chemical structure of corynebactinNot available
Average882.789Da
Monoisotopic882.2555585Da

Displaying 1–10 of 1589 metabolites