Finegoldia magna ATCC 29328

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Tissierellia

Order

Tissierellales

Family

Peptoniphilaceae

Genus

Finegoldia

Description

Finegoldia magna ATCC 29328 is a gram-positive, coccoid-shaped bacterium that thrives in anaerobic environments. This organism is classified as an obligate anaerobe, meaning it cannot survive in the presence of oxygen. It is a heterotroph, deriving its nutrients from organic compounds found in its environment. F. magna predominantly resides in the human microbiota, commonly found in various body sites, including the gastrointestinal tract, oral cavity, and occasionally in sterile sites during infections, such as abscesses. The coccoid shape of Finegoldia magna contributes to its ability to form clusters and withstand adverse conditions in anaerobic niches. Being a gram-positive bacterium, it possesses a thick peptidoglycan layer in its cell wall, which not only provides structural integrity but also plays a role in its pathogenic potential. The organism prefers a warm temperature range, aligning with the human body temperature, which facilitates its survival and growth in the host. As a heterotroph, F. magna metabolizes organic substrates for energy and carbon, which is crucial for its survival in the nutrient-rich environments of the mammalian body. Its role in the human microbiome is significant, as it is implicated in various aspects of health, including digestion and immune modulation. However, it can also be associated with opportunistic infections, particularly in individuals with compromised immune systems or disrupted microbiota. Research into F. magna has revealed its potential role in polymicrobial infections, particularly in wound infections and abscess formations. Understanding its interaction with other microbial species and its contributions to both health and disease continues to be a subject of interest in microbiological studies.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassTissierellia
OrderTissierellales
FamilyPeptoniphilaceae
GenusFinegoldia
SpeciesFinegoldia magna
StrainATCC 29328

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Finegoldia magna ATCC 29328
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Finegoldia magna ATCC 29328


Gene Summary

Adenine Count

601968 bp

Thymine Count

614762 bp

Guanine Count

286752 bp

Cytosine Count

294095 bp

Genome Length

1797577 bp

Protein-coding Genes

1655 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinFMG_RS08540Not Available-2204 - 269819477.1
relaxase/mobilization nuclease domain-containing proteinFMG_RS08545Not Available-2679 - 393249624.2
replication initiation proteinFMG_RS08550Not Available+4369 - 524735532.2
duf4176 domain-containing proteinFMG_RS08555Not Available+5240 - 54919849.73
rna-guided endonuclease insq/tnpb family proteinFMG_RS08560Not Available-7087 - 822344017.3
is200/is605 family transposaseFMG_RS08565Not Available-8162 - 862018038.7
hypothetical proteinFMG_RS08570Not Available-9156 - 946112182.5
hypothetical proteinFMG_RS08575Not Available-9620 - 98418656.35
hypothetical proteinFMG_RS08580Not Available-9998 - 1037514622.5
hypothetical proteinFMG_RS08585Not Available-10482 - 1086514974.3

Displaying genes 1 – 10 of 1907 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1646 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da

Displaying 1–10 of 1646 metabolites