Bacteroides fragilis YCH46

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis YCH46 is an anaerobic, Gram-negative, rod-shaped bacterium that thrives in human intestines, exhibiting a temperature preference for mesophilic conditions and functioning as a chemoheterotroph, utilizing organic compounds for energy production. This microbe is predominantly found in the gastrointestinal tract, where it plays a critical role in maintaining gut health, contributing to the complex microbiome that aids in digestion and nutrient absorption. As a mesophile, Bacteroides fragilis YCH46 grows optimally at moderate temperatures, which aligns with the conditions of the human body. Its classification as a chemoheterotroph indicates that it derives energy from organic substrates, metabolizing a variety of carbohydrates and proteins. This metabolic versatility allows it to thrive in the nutrient-rich environment of the intestines, where it can break down complex polysaccharides, contributing to the fermentation process and producing short-chain fatty acids that are beneficial for colon health. The Gram-negative characteristic of Bacteroides fragilis YCH46 is significant, as it possesses an outer membrane that contributes to its resistance against certain antibiotics. Its rod shape enhances its ability to colonize the intestinal mucosa, facilitating interactions with host tissues and other microbial species.Bacteroides fragilis YCH46 also plays a role in modulating the immune response, helping to maintain a balanced gut microbiota. An imbalance of this microbe has been associated with various gastrointestinal disorders, highlighting its importance in health and disease. Its ability to produce bacteriocins may also provide a competitive advantage against pathogenic bacteria, contributing to the overall stability of the gut ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainYCH46

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis YCH46
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Bacteroides fragilis YCH46

Accession NumberNC_006297.1

Gene Summary

Adenine Count

12182 bp

Thymine Count

10226 bp

Guanine Count

6525 bp

Cytosine Count

4783 bp

Genome Length

33716 bp

Protein-coding Genes

29670 genes

Non-Coding Genes

4046 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinBF_RS11085Not Available+2719540 - 272073344925.7
bacon domain-containing proteinBF_RS11090Not Available+2720831 - 272145421138.8
bacon domain-containing proteinBF_RS11095Not Available-2721510 - 272213620946.6
hypothetical proteinBF_RS11100Not Available+2722294 - 272272817313.6
AttrNot AvailableNot Available+2723062 - 2723074Not Available
hypothetical proteinBF_RS11105Not Available+2723342 - 272368012407.1
site-specific integraseBF_RS11110Not Available-2724849 - 272609348804.2
AttrNot AvailableNot Available+2726389 - 2726412Not Available
1_nc_021795: putative tail length tape measure proteinBF_RS11550Not Available-2832924 - 283513780213.6
hypothetical proteinBF_RS11555Not Available-2835130 - 28353849783.62

Displaying genes 81 – 90 of 1179 in total

Pathways

7 pathways

Metabolites

53 records
Metabolite IDMetabolite nameStructureCAS number
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002759dTDP-beta-L-rhamnoseC16H24N2O15P2Not availableNot available
Average546.316Da
Monoisotopic546.066289237Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0003448(4,5-dihydro-5-oxofuran-2-yl)-acetateC6H5O4Chemical structure of (4,5-dihydro-5-oxofuran-2-yl)-acetateNot available
Average141.103Da
Monoisotopic141.0193322Da
BASm0003671(S)-muconolactoneC6H5O4Chemical structure of (S)-muconolactoneNot available
Average141.103Da
Monoisotopic141.0193322Da
BASm0003721N-(6-aminohexanoyl)-6-aminohexanoateC12H24N2O3Chemical structure of N-(6-aminohexanoyl)-6-aminohexanoateNot available
Average244.335Da
Monoisotopic244.1786926Da
BASm0003949UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-uloseC17H25N3O16P2Chemical structure of UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-uloseNot available
Average589.3384Da
Monoisotopic589.0710048Da
BASm0003983di-trans,octa-cis-undecaprenyl phosphateC55H89O4PChemical structure of di-trans,octa-cis-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da

Displaying 1–10 of 53 metabolites