Staphylococcus aureus subsp. aureus MW2

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus aureus subsp. aureus MW2 is a gram-positive cocci bacterium that exhibits a staphylococcal arrangement, thrives optimally at temperatures around 37°C, is classified as a chemoheterotroph, and is a facultative anaerobe. This versatile microbe typically colonizes human skin and mucosal surfaces, including the nose, throat, and genitourinary tract, while also being associated with various infections in multiple body sites such as wounds, the bloodstream, respiratory tract, and bones. As a gram-positive organism, S. aureus MW2 retains crystal violet during the Gram staining process, resulting in a purple coloration indicative of its thick peptidoglycan cell wall. Its cocci shape allows for its characteristic formation into clusters, resembling bunches of grapes, which is a hallmark of staphylococci. The optimal growth temperature aligns with the human body temperature, facilitating its survival and proliferation within the host. Being a chemoheterotroph, S. aureus MW2 relies on organic compounds for both energy and carbon, which it derives from various substrates in its environment. This metabolic flexibility enables it to thrive in diverse environments, whether on skin or in other nutrient-rich niches. As a facultative anaerobe, it can grow in the presence or absence of oxygen, allowing it to switch between aerobic and anaerobic respiration based on environmental conditions. S. aureus MW2 is particularly noteworthy due to its ability to produce a wide array of virulence factors, including toxins and enzymes, which contribute to its pathogenicity. It is also known for its resistance to many antibiotics, making infections caused by this strain challenging to treat. The emergence of MRSA (Methicillin-resistant Staphylococcus aureus) strains, including MW2, raises significant public health concerns as these infections can lead to severe medical complications. Understanding this bacterium's behavior and resistance mechanisms is crucial for effective treatment and prevention strategies.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus aureus
StrainMW2

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus aureus subsp. aureus MW2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Staphylococcus aureus subsp. aureus MW2


Gene Summary

Adenine Count

942249 bp

Thymine Count

952267 bp

Guanine Count

463710 bp

Cytosine Count

462236 bp

Genome Length

2820462 bp

Protein-coding Genes

2560 genes

Non-Coding Genes

239 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Putative ribonucleaseMW_RS04045Not Available+836064 - 83843690360.7
Ssra-binding proteinMW_RS04050Not Available+838458 - 83892217756.7
Tmrna,resume;Not AvailableNot Available+839013 - 839371Not Available
AttlNot AvailableNot Available+839358 - 839372Not Available
hypothetical proteinMW_RS04055Not Available-839478 - 8396938455.2
Phage integraseMW_RS04060Not Available-839705 - 84081143811.5
Orf061MW_RS04065Not Available-840826 - 84156328978.1
Transcriptional regulatorMW_RS04070Not Available+841715 - 8419338334.21
hypothetical proteinMW_RS15220Not Available+841945 - 8420915385.79
Superantigen-encoding pathogenicity island proteinMW_RS04075Not Available+842084 - 8423088836.16

Displaying genes 1 – 10 of 2799 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

10 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014035Glycolic acidC2H4O3Chemical structure of Glycolic acid79-14-1
Average76.0514Da
Monoisotopic76.016043994Da
BASm0014036Glyoxylic acidC2H2O3Chemical structure of Glyoxylic acid298-12-4
Average74.0355Da
Monoisotopic74.00039393Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014042Oxoglutaric acidC5H6O5Chemical structure of Oxoglutaric acid328-50-7
Average146.0981Da
Monoisotopic146.021523302Da
BASm0039632Plasmodium bergheiNot available56-41-7Not available
BASm0039633Clostridium botulinumNot available56-87-1Not available
BASm0039638Streptococcus intermediusNot available74-79-3Not available
BASm0039639Staphylococcus intermediusNot available7440-09-7Not available

Displaying 1–10 of 10 metabolites