Klebsiella pneumoniae strain EuSCAPE_MK006

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_MK006 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans and various other hosts, including mammals and birds. This strain is classified as a chemoheterotroph, relying on organic compounds for energy, and it exhibits facultative anaerobic respiration, allowing it to thrive in both aerobic and anaerobic environments. The cellular arrangement of EuSCAPE_MK006 is characterized by chains, pairs, and singles, and it possesses flagella, which contributes to its motility. This organism is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for growth in the human body. Klebsiella pneumoniae is associated with a range of significant health effects, including bacteremia, urinary tract infections, pneumonia, and multiple other serious infections such as liver abscesses and meningitis. Its pathogenic potential highlights the importance of understanding its ecological interactions, particularly as it can exist in free-living states while also being a formidable human pathogen. The broad host range of EuSCAPE_MK006 includes not only Homo sapiens but also various species from the animal kingdom, including birds, amphibians, and mammals. This adaptability suggests a complex ecological role, where it can move between environments and hosts, potentially facilitating its spread and the emergence of antibiotic resistance. The strain's ability to cause diverse infections underscores the need for ongoing surveillance and research to mitigate its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_MK006

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_MK006
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_MK006 genome assembly,

Gene Summary

Adenine Count

1230292 bp

Thymine Count

1237499 bp

Guanine Count

1632447 bp

Cytosine Count

1640357 bp

Genome Length

5740595 bp

Protein-coding Genes

5241 genes

Non-Coding Genes

334 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3649585_00341Not AvailableNegative331401 - 33235436514.4
uncharacterised proteinSAMEA3649585_00342Not AvailablePositive332699 - 33297710083.0
antirestriction protein klcaSAMEA3649585_00343Not AvailablePositive333060 - 33345815147.6
uncharacterised proteinSAMEA3649585_00344Not AvailablePositive333556 - 33390312756.0
protein of uncharacterised function (duf3085)SAMEA3649585_00345Not AvailablePositive334006 - 33461122677.6
antirestriction proteinSAMEA3649585_00346Not AvailablePositive334695 - 33567536405.1
pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (e2) componentSAMEA3649585_00347Not AvailablePositive335810 - 33709948205.4
phage integraseSAMEA3649585_00348Not AvailablePositive337116 - 33806336966.9
Trna-pheNot AvailableNot AvailablePositive338281 - 338356Not Available
inner membrane protein yqgaSAMEA3649585_00350Not AvailableNegative338462 - 33917524623.6

Displaying genes 611 – 620 of 5575 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total