Klebsiella pneumoniae strain EuSCAPE_PL006

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL006 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism, making it capable of thriving in both aerobic and anaerobic environments. This strain is chemoheterotrophic, relying on organic compounds as its energy source. It typically occurs in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating its mobility. This strain is classified as mesophilic, with an optimal growth temperature of 37°C, which aligns with the typical human body temperature, suggesting its adaptation to host-associated habitats. K. pneumoniae is known to have a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoan and plant species, indicating its ecological versatility. K. pneumoniae strain EuSCAPE_PL006 is associated with numerous health complications, particularly in humans. It is implicated in serious infections such as bacteremia, pneumonia, urinary tract infections, and meningitis, among others. The strain's pathogenicity is a significant concern, as it can lead to severe health issues including sepsis and liver abscesses, especially in vulnerable populations. Notably, this strain does not undergo sporulation, which may influence its survival strategies and response to environmental stressors. The presence of only a single replicon and two membranes further underscores its classification within the Enterobacteriaceae family. Understanding the traits and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_PL006 contributes to insights into its role in human health and its ecological interactions within diverse environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL006

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL006
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL006


Gene Summary

Adenine Count

1176301 bp

Thymine Count

1178116 bp

Guanine Count

1578081 bp

Cytosine Count

1566848 bp

Genome Length

5499346 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
regulatorSAMEA3499936_04446Not AvailableNegative4757449 - 475794918738.5
inner membrane proteinSAMEA3499936_04447Not AvailableNegative4757946 - 475830813744.0
inner membrane proteinSAMEA3499936_04448Not AvailableNegative4758298 - 475864512717.1
maltose-6'-phosphate glucosidaseSAMEA3499936_04449Not AvailableNegative4758747 - 476006949258.0
pts family protein iicSAMEA3499936_04450Not AvailableNegative4760066 - 476168858376.2
hth-type transcriptional regulator yidpSAMEA3499936_04451Not AvailablePositive4761987 - 476270927223.1
mediator of hyperadherence yideSAMEA3499936_04452Not AvailableNegative4762701 - 476436258900.8
uncharacterised proteinSAMEA3499936_04453Not AvailablePositive4764742 - 47649126537.23
16 kda heat shock protein bSAMEA3499936_04454Not AvailableNegative4765423 - 476585115916.7
heat shock protein ibpaSAMEA3499936_04455Not AvailableNegative4765968 - 476638115706.6

Displaying genes 4511 – 4520 of 5198 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total