Klebsiella pneumoniae strain EuSCAPE_SK004

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK004 is a Gram-negative, rod-shaped bacterium that exhibits a variety of notable traits. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. It typically exists in chains, pairs, or as single cells, displaying mobility due to the presence of flagella. As a chemoheterotroph, it derives energy from organic compounds, and its optimal growth temperature is 37°C, placing it within the mesophilic range. EuSCAPE_SK004 is associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and vertebrates. This broad host range highlights its ecological versatility and potential for transmission across species. The strain is free-living, indicating it can survive independently outside of a host. Pathogenically, Klebsiella pneumoniae strain EuSCAPE_SK004 is known to cause multiple health issues, particularly in humans. It is associated with conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's ability to cause severe infections underscores its clinical significance, particularly in immunocompromised individuals. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_SK004 is crucial for addressing its impact on human health and developing strategies for infection control. Its adaptability and pathogenic potential highlight the need for ongoing surveillance and research in microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK004

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK004


Gene Summary

Adenine Count

1205175 bp

Thymine Count

1201054 bp

Guanine Count

1601025 bp

Cytosine Count

1614501 bp

Genome Length

5621755 bp

Protein-coding Genes

5092 genes

Non-Coding Genes

319 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
eca polymeraseSAMEA3500072_04172Not AvailableNegative4423078 - 442442451364.0
4-alpha-l-fucosyltransferaseSAMEA3500072_04173Not AvailableNegative4424421 - 442549740143.1
wzxe proteinSAMEA3500072_04174Not AvailableNegative4425494 - 442674444641.6
4-keto-6-deoxy-n-acetyl-d-hexosaminyl-(lipid carrier) aminotransferaseSAMEA3500072_04175Not AvailableNegative4426746 - 442787642214.7
lipopolysaccharide biosynthesis protein rffcSAMEA3500072_04176Not AvailableNegative4427882 - 442855624583.2
glucose-1-phosphate thymidylyltransferaseSAMEA3500072_04177Not AvailableNegative4428534 - 442941532798.5
dtdp-glucose 4,6-dehydrataseSAMEA3500072_04178Not AvailableNegative4429434 - 443050139667.7
udp-glucose dehydrogenaseSAMEA3500072_04179Not AvailableNegative4430498 - 443176045644.9
udp-n-acetylglucosamine 2-epimeraseSAMEA3500072_04180Not AvailableNegative4431757 - 443284240150.4
lipopolysaccharide biosynthesis protein wzzeSAMEA3500072_04181Not AvailableNegative4432944 - 443396038241.6

Displaying genes 4361 – 4370 of 5411 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total