Klebsiella pneumoniae strain EuSCAPE_PL034

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL034 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. It typically exhibits a variety of cell arrangements, including chains, pairs, and singles. This strain possesses flagella, allowing for mobility, and thrives optimally at 37°C within a mesophilic temperature range. Klebsiella pneumoniae is notably pathogenic to humans and has been associated with a wide range of health effects. These include bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections such as liver abscesses and pyonephrosis. The strain is also implicated in severe conditions like meningitis, sepsis, and neonatal sepsis. The ecological niche of this strain is primarily host-associated, having been identified in a diverse array of hosts, including Homo sapiens, Gallus gallus, and various other metazoan and plant species. This extensive host range suggests a high level of adaptability and potential for transmission across different environments and species. Klebsiella pneumoniae strain EuSCAPE_PL034 is nonsporulating and has a single replicon with a double membrane structure. Its ability to cause significant health problems, particularly in immunocompromised individuals, emphasizes the importance of understanding its biology and ecology. The strain's free-living nature, combined with its pathogenic potential, highlights the complexities of microbial interactions within host environments and the challenges in controlling its spread in both clinical and natural settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL034

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL034
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL034


Gene Summary

Adenine Count

1148640 bp

Thymine Count

1149736 bp

Guanine Count

1534562 bp

Cytosine Count

1551660 bp

Genome Length

5384598 bp

Protein-coding Genes

4794 genes

Non-Coding Genes

289 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphate starvation-inducible atpase phoh with rna binding motifSAMEA3499990_00446Not AvailablePositive481977 - 48302339207.1
metal-dependent hydrolase ybeySAMEA3499990_00447Not AvailablePositive483020 - 48349317684.9
magnesium and cobalt efflux protein corcSAMEA3499990_00448Not AvailablePositive483572 - 48451935950.3
apolipoprotein n-acyltransferaseSAMEA3499990_00449Not AvailablePositive484645 - 48618357605.9
glutamate and aspartate transporter subunitSAMEA3499990_00450Not AvailablePositive486538 - 48744933474.2
glutamate aspartate transport system permease protein gltjSAMEA3499990_00451Not AvailablePositive487614 - 48835427488.1
glutamate aspartate transport system permease protein gltkSAMEA3499990_00452Not AvailablePositive488354 - 48902824862.2
glutamate aspartate transport atp-binding protein gltlSAMEA3499990_00453Not AvailablePositive489028 - 48975326588.6
putative hemolysin activator hlybSAMEA3499990_00454Not AvailablePositive490127 - 49179762149.0
filamentous hemagglutininSAMEA3499990_00455Not AvailablePositive491863 - 49365661210.4

Displaying genes 691 – 700 of 5083 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total