Klebsiella pneumoniae strain EuSCAPE_SC001

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SC001 is a notable member of the Enterobacteriaceae family, characterized by its Gram-negative, rod-shaped morphology. This bacterium is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments, and it is classified as a chemoheterotroph, deriving energy from organic compounds. Its optimal growth temperature is 37°C, situating it within the mesophilic range, which is conducive to growth in human-associated habitats. The strain exhibits a variety of cell arrangements, appearing in chains, pairs, and singles, and it possesses flagella, indicating motility. EuSCAPE_SC001 maintains a unique biological relationship as a free-living organism, although it has significant interactions with various hosts, including Homo sapiens, Gallus gallus, and several other metazoan and plant species. Klebsiella pneumoniae strain EuSCAPE_SC001 is associated with a wide range of health complications, particularly in humans. It can cause serious conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The pathogenic potential of this strain underscores its relevance in clinical microbiology and public health. Ecologically, the presence of Klebsiella pneumoniae in diverse hosts, from humans to various animals and plants, reflects its adaptability and ability to thrive in different environments. This versatility may contribute to its role in both health and disease across multiple species, highlighting the importance of monitoring and understanding its behavior in ecological and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SC001

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SC001
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SC001


Gene Summary

Adenine Count

1193964 bp

Thymine Count

1195805 bp

Guanine Count

1601729 bp

Cytosine Count

1590341 bp

Genome Length

5581839 bp

Protein-coding Genes

5015 genes

Non-Coding Genes

365 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenine dna glycosylaseSAMEA3672979_00356Not AvailableNegative344495 - 34555339557.7
trna (guanine46-n7-)-methyltransferaseSAMEA3672979_00357Not AvailablePositive345690 - 34640927014.6
uncharacterized protein conserved in bacteriaSAMEA3672979_00358Not AvailablePositive346409 - 34673512819.2
protein of uncharacterised function (duf2884)SAMEA3672979_00359Not AvailablePositive346789 - 34750525935.9
radical sam proteinSAMEA3672979_00360Not AvailableNegative347546 - 34868242452.2
nucleoside 5-triphosphatase rdgbSAMEA3672979_00361Not AvailableNegative348675 - 34926820915.7
uncharacterised acr, yggu family cog1872SAMEA3672979_00362Not AvailableNegative349281 - 34957110294.7
integral membrane protein yggtSAMEA3672979_00363Not AvailableNegative349568 - 35013421093.3
alanine racemaseSAMEA3672979_00364Not AvailableNegative350155 - 35085625336.5
twitching motility protein piltSAMEA3672979_00365Not AvailablePositive350873 - 35185335232.9

Displaying genes 661 – 670 of 5380 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total