Klebsiella pneumoniae strain EuSCAPE_GR114

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR114 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe with the ability to thrive in various host-associated environments. This strain exhibits a chemoheterotrophic energy source and can be found in multiple cell arrangements, including chains, pairs, and singles. Notably, it possesses flagella, indicating mobility. Optimal growth occurs at 37°C, aligning with its mesophilic nature. This bacterium typically has a single replicon and is surrounded by two membranes, consistent with the structure of Gram-negative bacteria. EuSCAPE_GR114 has a diverse range of hosts, including Homo sapiens, various avian species, and other vertebrates, indicating its adaptability and potential for zoonotic transmission. Klebsiella pneumoniae is known for its pathogenicity in humans, leading to various health complications such as bacteremia, urinary tract infections, pneumonia, and a spectrum of other serious conditions, including sepsis and meningitis. The strain’s ability to cause infections in both humans and animals highlights its ecological versatility and potential impact on public health. Understanding the characteristics of EuSCAPE_GR114 is crucial for addressing its role in infectious diseases, particularly in clinical settings where it poses a risk for severe health outcomes. The strain's presence in multiple host species underscores the importance of monitoring its spread and developing strategies to mitigate its pathogenic effects across different environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR114

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR114
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR114


Gene Summary

Adenine Count

1339139 bp

Thymine Count

1339537 bp

Guanine Count

1726193 bp

Cytosine Count

1729694 bp

Genome Length

6134563 bp

Protein-coding Genes

5371 genes

Non-Coding Genes

502 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nitrilotriacetate monooxygenase component bSAMEA3649733_00277Not AvailableNegative288177 - 28879122534.6
ribosomal rna large subunit methyltransferase fSAMEA3649733_00278Not AvailablePositive288888 - 28980233897.4
potassium efflux system kefa protein / small-conductance mechanosensitive channelSAMEA3649733_00279Not AvailableNegative289805 - 29200080089.0
glutamate transport atp-binding proteinSAMEA3649733_00280Not AvailableNegative292112 - 29283426706.7
glutamate transport membrane-spanning proteinSAMEA3649733_00281Not AvailableNegative292831 - 29349024264.8
glutamine abc transporter periplasmic proteinSAMEA3649733_00282Not AvailableNegative293616 - 29436227153.5
non-specific dna-binding protein dps / iron-binding ferritin-like antioxidant protein / ferroxidaseSAMEA3649733_00283Not AvailableNegative294771 - 29527418709.3
dmt superfamily metabolite efflux proteinSAMEA3649733_00284Not AvailableNegative295512 - 29639931211.4
outer membrane protein xSAMEA3649733_00285Not AvailablePositive296751 - 29726318464.4
putative enzymeSAMEA3649733_00286Not AvailableNegative297354 - 29893459550.1

Displaying genes 771 – 780 of 5873 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total