Klebsiella pneumoniae strain EuSCAPE_PT085

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT085 is a gram-negative, rod-shaped bacterium categorized as a facultative anaerobe, enabling it to thrive in various oxygen environments. This strain is chemoheterotrophic, depending on organic compounds for energy. It typically forms chains, pairs, or exists as singles, demonstrating significant mobility due to the presence of flagella. EuSCAPE_PT085 is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, making it well-suited for colonization in hosts. Its habitat is primarily host-associated, indicating a strong relationship with various organisms, including Homo sapiens and several animal species such as Gallus gallus, Sus scrofa, and Canis lupus familiaris, among others. This strain exhibits a range of pathogenic effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The variety of health impacts underscores its potential as a significant opportunistic pathogen, particularly in immunocompromised individuals or those with underlying health issues. The ability of Klebsiella pneumoniae EuSCAPE_PT085 to inhabit diverse hosts and cause a wide range of infections highlights its ecological versatility and adaptability. This adaptability poses challenges for public health due to the potential for transmission between species and the increasing prevalence of antibiotic resistance. Understanding the traits and pathogenicity of this strain is crucial for developing targeted strategies to manage infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT085

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT085
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT085


Gene Summary

Adenine Count

1155790 bp

Thymine Count

1164085 bp

Guanine Count

1578312 bp

Cytosine Count

1546696 bp

Genome Length

5444883 bp

Protein-coding Genes

4857 genes

Non-Coding Genes

328 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane protein hemolysin iiiSAMEA3649899_00008Not AvailablePositive6641 - 730023790.1
putative global regulatorSAMEA3649899_00009Not AvailableNegative7451 - 843435636.4
ygfySAMEA3649899_00010Not AvailablePositive8680 - 894610481.6
inner membrane proteinSAMEA3649899_00011Not AvailablePositive8927 - 933716082.8
flavodoxin 2SAMEA3649899_00012Not AvailableNegative9344 - 986519543.1
tyrosine recombinase xerdSAMEA3649899_00013Not AvailablePositive9966 - 1086233969.1
thiol:disulfide interchange protein dsbcSAMEA3649899_00014Not AvailablePositive10885 - 1159825427.8
ssdna-specific exonuclease recjSAMEA3649899_00015Not AvailablePositive11604 - 1333762996.1
peptide chain release factor 2SAMEA3649899_00016Not AvailablePositive13559 - 1452135905.0
lysyl-trna synthetaseSAMEA3649899_00017Not AvailablePositive14531 - 1604857537.5

Displaying genes 281 – 290 of 5185 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total