Klebsiella pneumoniae strain EuSCAPE_PT049

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT049 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic respiration mode. This strain has a mobility feature, indicated by the presence of flagella, which allows it to move in various environments. It is a chemoheterotroph, indicating that it derives energy from organic compounds, and it thrives optimally at 37°C, placing it within the mesophilic temperature range. This bacterium is primarily host-associated, with documented relationships with a wide variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other metazoans and plants. Its biotic relationship is characterized as free-living, implying that it can survive independently in its environment. Klebsiella pneumoniae strain EuSCAPE_PT049 is notable for its pathogenicity in humans, being responsible for a range of serious health issues such as bacteremia, urinary tract infections, pneumonia, and various abdominal infections. It is linked to conditions like sepsis, neonatal sepsis, and pyogenic liver abscesses, among others. The broad spectrum of infections it can cause highlights its clinical significance and the potential for severe health impacts. The ability of this strain to inhabit multiple hosts, coupled with its pathogenicity, suggests a significant ecological role in disease transmission and persistence in various environments. Understanding the dynamics of Klebsiella pneumoniae strain EuSCAPE_PT049 could be critical for managing its impact on public health and for developing effective treatment strategies against the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT049

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT049
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT049


Gene Summary

Adenine Count

1189341 bp

Thymine Count

1192201 bp

Guanine Count

1584524 bp

Cytosine Count

1582805 bp

Genome Length

5548871 bp

Protein-coding Genes

5016 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein sprtSAMEA3649863_04270Not AvailableNegative4588480 - 458893818033.9
arabinose-proton symporterSAMEA3649863_04271Not AvailableNegative4589058 - 459045250871.5
s-adenosylmethionine synthetaseSAMEA3649863_04272Not AvailableNegative4590837 - 459199141909.9
arginine decarboxylaseSAMEA3649863_04273Not AvailablePositive4592833 - 459480973802.4
agmatinaseSAMEA3649863_04274Not AvailablePositive4595043 - 459596333515.9
peptidase m48 ste24pSAMEA3649863_04275Not AvailableNegative4596424 - 459718226848.8
maltoporinSAMEA3649863_04276Not AvailablePositive4597705 - 45978274562.32
2-aminoethylphosphonate abc transporter permease protein iiSAMEA3649863_04277Not AvailableNegative4598027 - 459882428363.5
2-aminoethylphosphonate abc transporter permeaseSAMEA3649863_04278Not AvailableNegative4598827 - 459968730969.3
2-aminoethylphosphonate abc transporter atp-binding proteinSAMEA3649863_04279Not AvailableNegative4599687 - 460079939980.7

Displaying genes 4281 – 4290 of 5196 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total