Klebsiella pneumoniae strain 1812100012 lung abscess API 5205773

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 1812100012 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain has mobility, facilitated by the presence of flagella, and is typically found in host-associated habitats, indicating its adaptation to living within various hosts. The bacterium is mesophilic, with an optimal growth temperature of 37°C. This strain is known to form chains, pairs, and singles, reflecting its unique cellular arrangement. It possesses a biotic relationship characterized as free-living, though it is also pathogenic to a range of hosts, including humans (Homo sapiens), various birds (Gallus gallus, Phasianidae), mammals (Canis lupus familiaris, Ovis aries, Sus scrofa), and other vertebrates, indicating its broad ecological niche. Klebsiella pneumoniae strain 1812100012 is associated with numerous health effects, primarily in humans, including bacteremia, urinary tract infections, pneumonia, liver abscesses, meningitis, and various intra-abdominal infections. Its pathogenicity is significant, as it can lead to severe conditions such as septicemia and early onset neonatal sepsis. The bacterium is nonsporulating and has a single replicon with a double membrane structure. The ecological insight from this data highlights the adaptability of Klebsiella pneumoniae strain 1812100012 to diverse hosts and environments, which may contribute to its persistence in clinical settings and its role as an opportunistic pathogen. Understanding its wide-ranging impact on health reinforces the importance of monitoring and controlling infections caused by this versatile microorganism.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 1812100012 lung abscess API 5205773

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 1812100012 lung abscess API 5205773
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 1812100012 lung abscess API 5205773


Gene Summary

Adenine Count

1148618 bp

Thymine Count

1156183 bp

Guanine Count

1567557 bp

Cytosine Count

1540651 bp

Genome Length

5413009 bp

Protein-coding Genes

5078 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aminomethyl-transferring glycine dehydrogenaseFCG27_26040Not AvailablePositive5210949 - 5213822104539.0
sdr family oxidoreductaseFCG27_26045Not AvailablePositive5213885 - 521462825661.8
transposaseFCG27_26050Not AvailablePositive5214709 - 52148264269.03
duf523 and duf1722 domain-containing proteinFCG27_26055Not AvailableNegative5215391 - 521635036410.3
duf3833 domain-containing proteinFCG27_26060Not AvailableNegative5216347 - 521689821042.0
hypothetical proteinFCG27_26065Not AvailableNegative5216895 - 521741919781.6
duf2878 domain-containing proteinFCG27_26070Not AvailableNegative5217416 - 521790117441.3
class i sam-dependent methyltransferaseFCG27_26075Not AvailableNegative5217898 - 521911846862.0
duf1365 domain-containing proteinFCG27_26080Not AvailableNegative5219115 - 521983728257.3
fad-dependent oxidoreductaseFCG27_26085Not AvailableNegative5219839 - 522109847134.1

Displaying genes 5121 – 5130 of 5336 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total