Escherichia coli strain DP254

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain DP254 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. The strain is mesophilic, with an optimal growth temperature of 37°C, which aligns closely with the body temperature of many warm-blooded hosts. This strain is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and Bos taurus, among others. Its biotic relationship is categorized as free-living, indicating its ability to exist independently of a host but also reflects its capacity to inhabit various environments associated with these hosts. Escherichia coli strain DP254 has been implicated in numerous health-related issues, primarily affecting the gastrointestinal and urinary systems of humans and animals. It is known to cause urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The range of health effects underscores its pathogenic nature, particularly in humans, where it can lead to serious complications like septicemia and renal failure. The extensive host range and the strain's ability to cause various diseases suggest its ecological versatility and role in both environmental and clinical settings. This adaptability may facilitate its transmission and persistence in different habitats, highlighting the importance of monitoring such strains in public health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain DP254

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain DP254
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain DP254


Gene Summary

Adenine Count

1296665 bp

Thymine Count

1296901 bp

Guanine Count

1331328 bp

Cytosine Count

1307948 bp

Genome Length

5232842 bp

Protein-coding Genes

5112 genes

Non-Coding Genes

251 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinC4K41_22690Not AvailablePositive4433566 - 44337697483.22
Putative dna methylaseC4K41_22695Not AvailablePositive4433920 - 443497240341.2
Putative holinC4K41_22700Not AvailablePositive4435040 - 44352557865.48
Hypothetical proteinC4K41_22705Not AvailablePositive4435260 - 443581120865.9
hypothetical proteinC4K41_22710Not AvailableNegative4435759 - 44360199521.4
EndolysinC4K41_22715Not AvailablePositive4436133 - 443666619551.5
Rz lysis proteinC4K41_22720Not AvailablePositive4436663 - 443713017085.6
Hypothetical proteinC4K41_22725Not AvailablePositive4437118 - 44372705840.41
Hypothetical proteinC4K41_22730Not AvailablePositive4437830 - 44379795760.76
Hypothetical proteinC4K41_22735Not AvailablePositive4437991 - 44381897212.89

Displaying genes 41 – 50 of 5363 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

120 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da

Displaying 1–10 of 120 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 74 in total