Klebsiella pneumoniae strain SCKP020003

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SCKP020003 is a Gram-negative, rod-shaped bacterium that primarily occupies host-associated environments. It functions as a chemoheterotroph, deriving energy from organic compounds. This strain exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic conditions. The optimal growth temperature for SCKP020003 is 37°C, placing it within the mesophilic temperature range. Morphologically, SCKP020003 can be found in various arrangements, including chains, pairs, and singles. It possesses flagella, which confer mobility, enhancing its ability to navigate through host environments. Notably, this strain has three replicons and a two-membrane system, characteristic of many Gram-negative bacteria. Klebsiella pneumoniae strain SCKP020003 is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae. It is known for its pathogenicity in humans, causing numerous health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The extensive list of infections associated with this strain underscores its clinical significance. This strain's ability to inhabit diverse ecological niches and its association with multiple hosts suggest that it plays a complex role in both human health and disease dynamics. Its pathogenic potential is particularly notable, emphasizing the need for ongoing surveillance and research to understand its impact on public health, especially given its capacity to cause severe infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SCKP020003

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SCKP020003
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SCKP020003


Gene Summary

Adenine Count

1378 bp

Thymine Count

1356 bp

Guanine Count

1301 bp

Cytosine Count

1561 bp

Genome Length

5596 bp

Protein-coding Genes

9 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Transposase is1CAY64_RS00910Not AvailableNegative95607 - 9602815266.2
Mazf-like proteinCAY64_RS00925Not AvailableNegative96277 - 9660911881.5
type ii toxin-antitoxin system antitoxin pemiCAY64_RS28920Not AvailableNegative96611 - 968689333.16
AttrNot AvailableNot AvailablePositive96875 - 96886Not Available
cpbp family intramembrane glutamic endopeptidaseCAY64_RS00930Not AvailableNegative96961 - 9761424308.9
AttlNot AvailableNot AvailablePositive97700 - 97712Not Available
incfii family plasmid replication initiator repaCAY64_RS00940Not AvailableNegative98553 - 9941032679.5
repa leader peptide tapCAY64_RS30840Not AvailableNegative99403 - 994772661.29
replication regulatory protein repaCAY64_RS00955Not AvailableNegative99722 - 999709022.86
Host killer proteinCAY64_RS00960Not AvailableNegative100254 - 1004035543.0

Displaying genes 41 – 50 of 5608 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total