Akkermansia muciniphila strain EB-AMDK-18

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain EB-AMDK-18 is a Gram-negative, coccoid bacterium that typically exists in pairs or as single cells, demonstrating its adaptation to a host-associated habitat. This strain thrives at an optimal temperature of 37.0°C, reflecting its role within warm-blooded host environments. As an anaerobic organism, it requires an oxygen-free environment for growth and metabolism, which is consistent with its presence in mucosal layers of the gastrointestinal tract. The unique morphological characteristics of Akkermansia muciniphila, specifically its cocci shape and arrangement, contribute to its ecological niche in the host's microbiome. This strain is of particular interest due to its potential contributions to gut health, as it is known to interact with host mucins, suggesting a role in maintaining mucosal integrity and influencing metabolic processes. The ability of this bacterium to thrive in anaerobic conditions within the host may also be indicative of its evolutionary adaptations to the gut environment. In summary, Akkermansia muciniphila strain EB-AMDK-18 exemplifies a specialized anaerobic organism that plays a significant role in the host-associated microbiome, potentially impacting the host's health through its interactions with mucosal layers and associated metabolic functions.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain EB-AMDK-18

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain EB-AMDK-18
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-18


Gene Summary

Adenine Count

618995 bp

Thymine Count

619226 bp

Guanine Count

768563 bp

Cytosine Count

763340 bp

Genome Length

2770124 bp

Protein-coding Genes

2311 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
chromosomal replication initiator protein dnaaC1O57_RS00005Not Available+1 - 140752337.4
abc transporter atp-binding proteinC1O57_RS00010Not Available+1566 - 250134597.0
abc transporter permease subunitC1O57_RS00015Not Available+2555 - 333729672.2
gldg family proteinC1O57_RS00020Not Available+3376 - 494759608.7
duf4340 domain-containing proteinC1O57_RS00025Not Available+4976 - 703076450.4
nif3-like dinuclear metal center hexameric proteinC1O57_RS00030Not Available+7044 - 782327350.6
rlua family pseudouridine synthaseC1O57_RS00035Not Available+7840 - 881135048.9
prephenate dehydrataseC1O57_RS00040Not Available+9184 - 1034142996.4
alpha-l-fucosidaseC1O57_RS00045Not Available+10400 - 1201659365.7
nad-dependent dna ligase ligaC1O57_RS00050Not Available+12041 - 1442586293.2

Displaying genes 1 – 10 of 2376 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites