Bifidobacterium breve strain N6D12 C1090

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain N6D12 C1090 is a Gram-positive, anaerobic bacterium commonly found in diverse habitats, including human breast milk and the gastrointestinal tracts of healthy newborns. This strain is notably a member of the infant gut microbiota, contributing to the microbial ecosystem of the infant intestine. Its presence in breast milk indicates its potential role in establishing beneficial gut flora during early development, which is crucial for the overall health and immune function of infants. As an anaerobic organism, B. breve N6D12 C1090 thrives in low-oxygen environments, which is characteristic of the gastrointestinal tract and aligns with its adaptation to colonize the human gut. The strain's ability to inhabit both breast milk and the intestines suggests a dynamic interaction between maternal and infant microbiomes, potentially influencing the infant's digestive health and immune responses. This strain's prevalence in the microbiota of healthy newborns underscores its significance in early microbial colonization and suggests that it may play a role in the development of a balanced gut microbiome. In addition, the presence of B. breve N6D12 C1090 in breast milk may provide essential prebiotics that support the growth of beneficial bacteria in infants, highlighting its importance in promoting gut health from the very beginning of life. Further research on this strain could elucidate its specific contributions to gut health and its potential applications in probiotic therapies.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain N6D12 C1090

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain N6D12 C1090


Gene Summary

Adenine Count

466364 bp

Thymine Count

464456 bp

Guanine Count

661580 bp

Cytosine Count

664871 bp

Genome Length

2290315 bp

Protein-coding Genes

1896 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
cell filamentation protein ficCE164_00005Not Available-151 - 99331743.7
dna-binding proteinCE164_00010Not Available-1675 - 262836320.3
hypothetical proteinCE164_00015Not Available-3213 - 34137359.24
site-specific integraseCE164_00020Not Available+3979 - 532251759.0
dna topoisomerase iiiCE164_00025Not Available-5527 - 772581094.8
gas vesicle proteinCE164_00030Not Available-7745 - 817615618.7
hypothetical proteinCE164_00035Not Available+8607 - 890011351.2
hypothetical proteinCE164_00045Not Available+9405 - 969211107.1
hypothetical proteinCE164_00050Not Available+9709 - 99579326.32
plasmid mobilization relaxosome protein mobcCE164_00055Not Available+10406 - 1078614957.5

Displaying genes 1 – 10 of 1952 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites