Helicobacter pylori UM037

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori UM037 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, which aligns with the typical physiological conditions found within its host environment. H. pylori UM037 is predominantly associated with the gastric mucosa of its host, where it can inhabit and adapt to the unique microenvironment of the stomach, including its varied pH levels. As a microaerophilic organism, H. pylori UM037 requires reduced levels of oxygen for growth, which is consistent with its adaptation to the oxygen-limited conditions present in the gastric niche. The bacterium's spiral shape facilitates motility, allowing it to navigate the viscous environment of gastric mucus and colonize the epithelial lining effectively. The habitat of H. pylori UM037 suggests a specialized ecological role, as it may influence the gastric microbiome and interact with host immune responses. Understanding the specific traits of H. pylori UM037 can provide insights into its ecological significance and potential implications for host health, particularly in relation to gastric conditions. Further studies on this strain could elucidate its functional roles within the host-associated microbiota and its contributions to the overall microbial diversity in the gastric environment.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainUM037

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori UM037
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori UM037


Gene Summary

Adenine Count

516999 bp

Thymine Count

517414 bp

Guanine Count

323316 bp

Cytosine Count

335065 bp

Genome Length

1692794 bp

Protein-coding Genes

1567 genes

Non-Coding Genes

78 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Gp26K750_RS01895Not Available-384573 - 38527727537.5
hd domain-containing proteinK750_RS01900Not Available-385277 - 38649747318.2
Hypothetical proteinK750_RS01905Not Available+386919 - 3871799549.1
AttlNot AvailableNot Available+386961 - 386974Not Available
Putative integraseK750_RS01910Not Available+387179 - 38830043107.7
Hypothetical proteinK750_RS01915Not Available+388297 - 3885158531.34
hypothetical proteinK750_RS08670Not Available+388517 - 3886846230.01
Hypothetical proteinK750_RS01920Not Available+388686 - 38961836301.8
Hypothetical proteinK750_RS01925Not Available+389636 - 38999214428.8
Putative dna helicase, putative dna repair proteinK750_RS01930Not Available+390102 - 39128045580.8

Displaying genes 1 – 10 of 1645 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

21 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00019773,4-dihydroxybenzoateC7H5O4Chemical structure of 3,4-dihydroxybenzoateNot available
Average153.114Da
Monoisotopic153.019332221Da
BASm0002759dTDP-beta-L-rhamnoseC16H24N2O15P2Not availableNot available
Average546.316Da
Monoisotopic546.066289237Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm00030222-methyl-cis-aconitateC7H5O6Chemical structure of 2-methyl-cis-aconitateNot available
Average185.113Da
Monoisotopic185.0102586Da
BASm0003334aldehydo-D-ribose 5-phosphateC5H11O8PChemical structure of aldehydo-D-ribose 5-phosphateNot available
Average230.1098Da
Monoisotopic230.0191538Da

Displaying 1–10 of 21 metabolites