Mycobacterium tuberculosis str. Erdman = ATCC 35801

Gram-positiveRodNon-motileAerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium tuberculosis strain Erdman (ATCC 35801) is a Gram-positive, rod-shaped bacterium that typically occurs as single cells. This strain is a member of the Mycobacterium genus and is characterized by its aerobic metabolism, requiring oxygen for growth. Optimal growth occurs at a temperature of 37.0°C, which aligns with its adaptation to the human host environment. As a chemoorganotroph, M. tuberculosis Erdman utilizes organic compounds as its energy source, which is reflective of its nutritional requirements in host-associated habitats. The bacterium's unique cell wall composition, rich in mycolic acids, contributes to its resilience in hostile environments and plays a critical role in its pathogenicity, although specific pathogenic traits are not discussed here. The ecological niche of M. tuberculosis Erdman is primarily associated with human hosts, indicating a specialized adaptation to a parasitic lifestyle. This association highlights the potential for co-evolution between the microbe and its human host, wherein the bacterium has developed mechanisms to evade the host immune response while relying on the host's metabolic resources for survival. Understanding the specific adaptations of this strain can provide insights into the broader ecological dynamics of Mycobacterium tuberculosis within human populations.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium tuberculosis
StrainErdman = ATCC 35801

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Mycobacterium tuberculosis str. Erdman = ATCC 35801
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Mycobacterium tuberculosis str. Erdman = ATCC 35801


Gene Summary

Adenine Count

755858 bp

Thymine Count

756731 bp

Guanine Count

1436491 bp

Cytosine Count

1443273 bp

Genome Length

4392353 bp

Protein-coding Genes

4083 genes

Non-Coding Genes

72 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+2958304 - 2958324Not Available
IntegraseERDMAN_RS13960Not Available+2958792 - 295979036592.1
Hypothetical proteinERDMAN_RS13965Not Available+2959804 - 296026817306.5
hypothetical proteinERDMAN_RS13970Not Available+2960256 - 29605078885.1
Major capsid proteinERDMAN_RS13975Not Available-2960678 - 296211751090.5
Prohead proteinERDMAN_RS13980Not Available-2962125 - 296265819293.2
Terminase small subunitERDMAN_RS21695Not Available-2962811 - 296330217267.6
type ii toxin-antitoxin system toxinERDMAN_RS13990Not Available-2963469 - 296379212360.5
type ii toxin-antitoxin system antitoxinERDMAN_RS13995Not Available-2963872 - 29641177698.1
duf3631 domain-containing proteinERDMAN_RS14000Not Available-2964114 - 296554151720.9

Displaying genes 1 – 10 of 4155 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites