Gardnerella vaginalis ATCC 14019

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis (strain 409-05) is a facultative anaerobic Gram-variable bacterium. It is the most prevalent sexually transmitted organism and is associated with bacterial vaginosis (BV) in which the normal lactobacilli microbiota is replaced by relatively high concentrations of other bacteria, especially G. vaginalis. It reflects a complex alteration of the vaginal microbiota, normally in the absence of inflammatory response. It generally leads to the presence of intense discharges in the absence of itching, burning sensations or urinary symptoms. G. vaginalis was found to be a risk factor for the acquisition of human immunodeficiency virus (HIV), in which stimulation of HIV expression by G. vaginalis was demonstrated. This bacterium is also associated with bacteraemia, urinary track infections, and neonatal meningitis. (Adaptated from PMID: 20221621). (EBI Integr8)

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
StrainATCC 14019

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis ATCC 14019
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityYes

Genome Summary

Gardnerella vaginalis ATCC 14019


Gene Summary

Adenine Count

488860 bp

Thymine Count

488822 bp

Guanine Count

347339 bp

Cytosine Count

342329 bp

Genome Length

1667350 bp

Protein-coding Genes

1272 genes

Non-Coding Genes

54 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinHMPREF0421_RS00005Not Available-67 - 79824602.4
f0f1 atp synthase subunit epsilonHMPREF0421_RS00010Not Available-1420 - 173411168.5
f0f1 atp synthase subunit betaHMPREF0421_RS00015Not Available-1737 - 322453918.7
f0f1 atp synthase subunit gammaHMPREF0421_RS00020Not Available-3231 - 423536613.1
f0f1 atp synthase subunit alphaHMPREF0421_RS00025Not Available-4239 - 590059944.7
fof1 atp synthase subunit deltaHMPREF0421_RS00030Not Available-5918 - 649921334.4
f0f1 atp synthase subunit bHMPREF0421_RS00035Not Available-6575 - 711719693.4
atp synthase f0 subunit cHMPREF0421_RS00040Not Available-7178 - 74118007.19
f0f1 atp synthase subunit aHMPREF0421_RS00045Not Available-7502 - 836231551.9
Trna-metNot AvailableNot Available+8743 - 8816Not Available

Displaying genes 1 – 10 of 1326 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites