Mobiluncus curtisii ATCC 43063

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Mobiluncus

Description

Bacterial vaginosis (BV) is a common cause of abnormal vaginal discharge. It is characterised by an overgrowth of predominantly anaerobic organisms (Gardnerella vaginalis, Prevotella spp., Peptostreptocci, Mobiluncus spp.) in the vagina leading to a replacement of lactobacilli and an increase in vaginal pH. BV can arise and remit spontaneously, but often presents as a chronic or recurrent disease. BV is found most often in women of childbearing age, but may also be encountered in menopausal women, and is rather rare in children Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) is an anaerobic, rod shaped Gram-positive bacterium found in the human vagina. (adapted from: http://www.ncbi.nlm.nih.gov/genomeprj/31519 and PMID: 20723268). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Actinomycetota
Class	Actinomycetes
Order	Actinomycetales
Family	Actinomycetaceae
Genus	Mobiluncus
Species	Mobiluncus curtisii
Strain	ATCC 43063

Profile

Physiology
Gram staining properties	Positive
Shape	Rod
Mobility	Not Available
Flagellar presence	Not Available
Number of membranes	Not Available

Ecology, Host, and Life Cycle
Oxygen requirements	Anaerobe
Optimal temperature	Not Available
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens
Cell arrangement	Not Available
Sporulation	Not Available
Energy source	Not Available
Pathogenicity	Not Available

Genome Summary

Mobiluncus curtisii ATCC 43063

Accession NumberNC_014246.1

Gene Summary

Adenine Count

479617 bp

Thymine Count

477428 bp

Guanine Count

591728 bp

Cytosine Count

597707 bp

Genome Length

2146480 bp

Protein-coding Genes

1787 genes

Non-Coding Genes

98 genes

# of Chromosomes/Plasmids

1

Genes

Name	Locus Tag	UniProt	Strand	Coordinates	Molecular Weight
abc transporter atp-binding protein	HMPREF0573_RS01825	Not Available	+	427259 - 427963	25441.3
cbs and act domain-containing protein	HMPREF0573_RS01830	Not Available	+	427984 - 428604	22376.1
homoserine kinase	HMPREF0573_RS01835	Not Available	-	428731 - 429636	31770.9
threonine synthase	HMPREF0573_RS01840	Not Available	-	429708 - 430847	39547.5
homoserine dehydrogenase	HMPREF0573_RS01845	Not Available	-	430946 - 432241	45245.1
hypothetical protein	HMPREF0573_RS09765	Not Available	-	432266 - 432421	5780.97
arginine--trna ligase	HMPREF0573_RS01850	Not Available	-	432422 - 434101	60210.8
Trna-arg	Not Available	Not Available	+	434208 - 434280	Not Available
nramp family divalent metal transporter	HMPREF0573_RS01860	Not Available	-	434332 - 435588	43488.5
hypothetical protein	HMPREF0573_RS01865	Not Available	-	435657 - 436046	13910.4

Displaying genes 441 – 450 of 1885 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolite ID	Metabolite name	Structure	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P		Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000251	2-dehydropantoateC6H9O4		Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000377	(S)-malateC4H4O5		Not available	Average132.0716Da Monoisotopic132.005873238Da
BASm0000989	GlycerolC3H8O3		`56-81-5`	Average92.0938Da Monoisotopic92.04734412Da
BASm0001035	indole-3-pyruvateC11H8NO3		`35656-49-6`	Average202.1861Da Monoisotopic202.0504181Da
BASm0001167	triphosphateO10P3		`14127-68-5`	Average252.9153Da Monoisotopic252.8704308Da
BASm0001639	CobinamideC48H72CoN11O8		`13497-85-3`	Average990.0874Da Monoisotopic989.4897335Da
BASm0001661	Cu(2+)Cu		`7440-50-8`	Average63.546Da Monoisotopic62.929601079Da
BASm0002197	D-arabinoseC5H10O5		Not available	Average150.1299Da Monoisotopic150.05282343Da
BASm0002241	2-demethylmenaquinone-8C50H70O2		Not available	Average703.0896Da Monoisotopic702.5375815Da

Displaying 1–10 of 220 metabolites