Gardnerella vaginalis 409-05

Gardnerella vaginalis (strain 409-05) is a facultative anaerobic Gram-variable bacterium. It is the most prevalent sexually transmitted organism and is associated with bacterial vaginosis (BV) in which the normal lactobacilli microbiota is replaced by relatively high concentrations of other bacteria, especially G. vaginalis. It reflects a complex alteration of the vaginal microbiota, normally in the absence of inflammatory response. It generally leads to the presence of intense discharges in the absence of itching, burning sensations or urinary symptoms. G. vaginalis was found to be a risk factor for the acquisition of human immunodeficiency virus (HIV), in which stimulation of HIV expression by G. vaginalis was demonstrated. This bacterium is also associated with bacteraemia, urinary track infections, and neonatal meningitis. (Adaptated from PMID: 20221621). (EBI Integr8)