Helicobacter pylori strain 22211

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22211 is a Gram-negative bacterium characterized by its distinctive spirilla shape and single-cell arrangement. This microbe thrives optimally at 37.0°C, which aligns with the human body temperature, suggesting its adaptation to a host-associated habitat. As a microaerophilic organism, H. pylori strain 22211 requires reduced levels of oxygen for growth, indicating a specialized niche within the gastrointestinal tract where oxygen levels are lower than atmospheric concentrations. The microbe's unique morphological and physiological traits contribute to its survival and potential interactions within the host environment. The spiral shape may facilitate motility through the viscous mucus layer of the stomach, allowing it to colonize the gastric epithelium effectively. Additionally, its Gram-negative cell structure may provide a robust outer membrane that contributes to its resilience against the acidic conditions of the gastric environment. The habitat preference for host-associated environments suggests that H. pylori strain 22211 may play a role in the complex interplay of microbial communities within the human gut. This strain's microaerophilic requirement highlights the importance of localized oxygen gradients in microbial ecology, potentially influencing the broader dynamics of microbial interactions in the gastrointestinal ecosystem. Understanding the specific traits of H. pylori strain 22211 can provide insights into its ecological role and adaptive strategies within its host.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 22211

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 22211
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22211


Gene Summary

Adenine Count

511535 bp

Thymine Count

515421 bp

Guanine Count

323376 bp

Cytosine Count

329103 bp

Genome Length

1679435 bp

Protein-coding Genes

1496 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
16s ribosomal rnaNot AvailableNot AvailablePositive502 - 2011Not Available
hypothetical proteinBB431_00020Not AvailableNegative1427 - 177414051.5
cell division proteinBB431_00025Not AvailableNegative1776 - 219516310.3
5-amino-6-(5-phosphoribosylamino)uracil reductaseBB431_00030Not AvailableNegative2165 - 355353600.6
type vii secretion proteinBB431_00035Not AvailableNegative3564 - 382410372.0
hypothetical proteinBB431_00040Not AvailableNegative3840 - 440921666.9
hypothetical proteinBB431_00045Not AvailableNegative4406 - 684493030.8
hypothetical proteinBB431_00055Not AvailableNegative7464 - 782614039.6
hypothetical proteinBB431_00060Not AvailableNegative8666 - 88757636.08
1-pyrroline-5-carboxylate dehydrogenaseBB431_00065Not AvailablePositive9204 - 12761135064.0

Displaying genes 1 – 10 of 1539 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 66 in total