Helicobacter pylori strain 3053

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3053 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe thrives in microaerophilic conditions, indicating a specific requirement for reduced oxygen levels, which is typical for members of the Helicobacter genus. The optimal growth temperature for strain 3053 is approximately 37.0°C, aligning with the physiological temperature of the human host, which suggests its adaptation to a host-associated habitat. As a member of the Helicobacter genus, strain 3053 is typically found in the gastric environment of mammals, where it might play a role in specific digestive processes. Its microaerophilic nature likely facilitates its survival in the gastric niche, where oxygen levels are lower than in the external environment but are essential for its metabolic functions. The presence of this strain in the host-associated habitat reflects the evolutionary adaptations of Helicobacter species to persist in the acidic conditions of the stomach. Understanding the specific traits of Helicobacter pylori strain 3053 can provide insights into its ecological role in the gastric microbiota, particularly in relation to its interactions with the host's immune system and potential influences on gastrointestinal health. Further research may elucidate the implications of its unique physiological characteristics in relation to host-microbe interactions and overall gut ecology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 3053

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 3053
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3053


Gene Summary

Adenine Count

493336 bp

Thymine Count

489887 bp

Guanine Count

321095 bp

Cytosine Count

306319 bp

Genome Length

1610637 bp

Protein-coding Genes

1424 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinBB453_00005Not Available-136 - 51914579.0
16s ribosomal rnaNot AvailableNot Available+803 - 2312Not Available
sodium:proton antiporterBB453_00015Not Available+3713 - 481939978.9
lipopolysaccharide biosynthesis proteinBB453_00020Not Available-4833 - 586440276.8
lipopolysaccharide 1,2-glucosyltransferaseBB453_00025Not Available-5888 - 60014242.15
hypothetical proteinBB453_00030Not Available+6158 - 751052539.6
5s ribosomal rnaNot AvailableNot Available+6834 - 6951Not Available
23s ribosomal rnaNot AvailableNot Available+7181 - 10066Not Available
molecular chaperone htpgBB453_00035Not Available+7613 - 947871352.3
sel1 repeat protein hcpaBB453_00040Not Available-9687 - 1043927325.0

Displaying genes 1 – 10 of 1466 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

31 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001767oxalateC2O4Chemical structure of oxalateNot available
Average88.019Da
Monoisotopic87.979658488Da
BASm0001785(2R,3R)-tartrateC4H6O6Chemical structure of (2R,3R)-tartrate87-69-4
Average150.0868Da
Monoisotopic150.0164379Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002131(3S)-hydroxy-3-methylglutaryl-CoAC27H39N7O20P3SChemical structure of (3S)-hydroxy-3-methylglutaryl-CoANot available
Average906.62Da
Monoisotopic906.1183419Da

Displaying 1–10 of 31 metabolites