Helicobacter pylori CCHI 33

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori CCHI 33 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and solitary cell arrangement. This organism thrives optimally at 37.0°C, which aligns with the physiological temperature of its host environments, indicating that it is well-adapted to living within the gastric niche of mammals. As a host-associated microbe, H. pylori CCHI 33 plays a significant role in the complex microbial communities found in the gastrointestinal tract. Its microaerophilic nature suggests that it requires reduced oxygen levels for growth, which is consistent with the oxygen gradients present in the stomach. This adaptation allows H. pylori to occupy a unique ecological niche where it can interact with both the host and other microbial inhabitants of the gastrointestinal tract. The ability of H. pylori to maintain its viability and metabolic activity in the acidic environment of the stomach may provide insights into its ecological role in influencing gastric health and disease. Understanding H. pylori CCHI 33's specific adaptations and interactions within its host-associated habitat may further elucidate its potential contributions to the human microbiome and its relationship with various gastrointestinal conditions.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainCCHI 33

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori CCHI 33
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori CCHI 33


Gene Summary

Adenine Count

502748 bp

Thymine Count

506362 bp

Guanine Count

324600 bp

Cytosine Count

325616 bp

Genome Length

1659327 bp

Protein-coding Genes

1656 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinA608_0001Not Available+383 - 5024694.99
23s ribosomal rnaNot AvailableNot Available+765 - 3651Not Available
5s ribosomal rnaNot AvailableNot Available+3891 - 4006Not Available
hypothetical proteinA608_0004Not Available+4013 - 42107572.46
yihy family inner membrane domain proteinA608_0005Not Available-4237 - 511534616.7
biotin synthaseA608_0006Not Available-5115 - 596331477.8
putative type iii restriction enzyme r proteinA608_0007Not Available+6094 - 62194920.84
dead/deah box helicase family proteinA608_0008Not Available+6375 - 873892502.9
dna methylase family proteinA608_0009Not Available+8732 - 1020156499.1
methylase domain proteinA608_0010Not Available+10304 - 1059411356.4

Displaying genes 1 – 10 of 1697 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

166 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da

Displaying 1–10 of 166 metabolites