Helicobacter pylori Hp P-4c

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp P-4c is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement, thriving in microaerophilic conditions at an optimal temperature of 37.0°C. This microbe is primarily host-associated, indicating a close relationship with its ecological niche, typically found in the gastric mucosa of mammals. The microaerophilic nature of H. pylori Hp P-4c suggests it requires reduced oxygen levels for optimal growth, which aligns with its habitat within the stomach, where oxygen concentration is lower than in the external environment. The ability to flourish in such conditions underscores its adaptation to the unique biochemical milieu of the gastric environment. Understanding the traits of H. pylori Hp P-4c can provide insights into its role within the host and its potential interactions with the host's immune system and microbiome. The microaerophilic lifestyle, combined with its specific temperature preference, may influence its metabolic pathways and enzymatic activities, contributing to its survival and persistence in the gastric habitat. This adaptation might also reflect broader ecological interactions within the gastrointestinal tract, where such specialized microorganisms can play significant roles in digestion and health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp P-4c

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp P-4c
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp P-4c


Gene Summary

Adenine Count

510969 bp

Thymine Count

514049 bp

Guanine Count

328546 bp

Cytosine Count

329745 bp

Genome Length

1683310 bp

Protein-coding Genes

1662 genes

Non-Coding Genes

78 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
3,4-dihydroxy-2-butanone 4-phosphate synthaseHPHPP4C_1064O25484-1053275 - 105430939023.2
Hypothetical proteinHPHPP4C_1065Not Available+1054635 - 105500613670.0
AttlNot AvailableNot Available+1054772 - 1054784Not Available
Integrase/recombinaseHPHPP4C_1066P96629+1055116 - 105626444501.4
Hypothetical proteinHPHPP4C_1067Not Available+1056261 - 10564678220.06
Putative transcriptional regulatorHPHPP4C_1068Not Available+1056469 - 105677712126.8
Hypothetical proteinHPHPP4C_1069Not Available+1056774 - 105774237752.5
Hypothetical proteinHPHPP4C_1070Not Available+1057939 - 105820810797.5
Dna repair proteinHPHPP4C_1071Not Available+1058218 - 105851111302.7
TransposaseHPHPP4C_1072Not Available-1058480 - 105976349333.8

Displaying genes 1 – 10 of 1740 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da

Displaying 1–10 of 93 metabolites