Helicobacter pylori Hp A-27

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain Hp A-27 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe thrives optimally at 37.0°C, which aligns with the typical body temperature of its human hosts. As a microaerophilic organism, H. pylori Hp A-27 requires reduced levels of oxygen for growth, indicating its adaptation to the specific environmental conditions found in the human stomach, where it resides as a host-associated organism. The spirilla morphology of H. pylori Hp A-27 is significant, as it contributes to the bacterium's motility, enabling it to navigate the viscous gastric environment. The microbe's capability to survive in the acidic conditions of the stomach is facilitated by its unique enzymatic systems, although specific mechanisms for this strain have not been delineated here. Overall, the ecological niche of H. pylori Hp A-27 reflects its specialized adaptation to a microaerobic and acidic environment, highlighting the complex interactions that exist between host physiology and microbial life in the gastrointestinal tract. This relationship underscores the potential for further investigation into how specific strains like Hp A-27 may influence host health and disease states through their metabolic activities and environmental adaptations.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp A-27

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp A-27
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp A-27


Gene Summary

Adenine Count

500573 bp

Thymine Count

509824 bp

Guanine Count

318644 bp

Cytosine Count

323059 bp

Genome Length

1652101 bp

Protein-coding Genes

1666 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
urease accessory protein uregHPHPA27_0021Not AvailableNegative17819 - 1841821956.6
urease accessory protein urefHPHPA27_0022Not AvailableNegative18447 - 1921128680.5
urease accessory protein ureeHPHPA27_0023Not AvailableNegative19235 - 1974719500.8
acid-activated urea channelHPHPA27_0024Not AvailableNegative19749 - 2032121197.0
urease, alpha subunitHPHPA27_0025Not AvailableNegative20529 - 2223861687.2
urease subunit alphaHPHPA27_0026Not AvailableNegative22242 - 2295826541.1
Trna-valNot AvailableNot AvailablePositive23213 - 23288Not Available
signal peptidase iiHPHPA27_0028Not AvailableNegative23306 - 2377917865.4
phosphoglucosamine mutaseHPHPA27_0029Not AvailableNegative23773 - 2511049184.5
ribosomal protein s20HPHPA27_0030Not AvailablePositive25200 - 2546910210.7

Displaying genes 21 – 30 of 1707 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.