Helicobacter pylori Hp A-16

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain Hp A-16 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with the physiological conditions of its primary habitat, the human stomach. As a microaerophilic organism, H. pylori Hp A-16 requires reduced levels of oxygen for growth, reflecting its adaptation to the gastric environment where oxygen levels are limited. H. pylori is notably associated with the host, residing in the gastric mucosa, and it plays a significant role in the complex interactions between the microbiota and the host's gastrointestinal system. The unique combination of its morphological traits and specific oxygen requirements underscores its evolutionary adaptations to survive in the harsh acidic environment of the stomach. An intriguing aspect of H. pylori Hp A-16’s biology is its potential role in shaping the gastric microbiome, which may influence not only digestive health but also broader systemic effects on the host. Understanding the specific traits of this strain can contribute to insights into the dynamics of host-associated microbial communities and their implications for human health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp A-16

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp A-16
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp A-16


Gene Summary

Adenine Count

495220 bp

Thymine Count

500779 bp

Guanine Count

318910 bp

Cytosine Count

322891 bp

Genome Length

1637800 bp

Protein-coding Genes

1662 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+470 - 585Not Available
hypothetical proteinHPHPA16_0002Not Available+592 - 7144850.3
yihy family proteinHPHPA16_0003Not Available-1115 - 199334577.7
biotin synthaseHPHPA16_0004Q9ZJK8-1993 - 284131491.8
hypothetical proteinHPHPA16_0005Not Available+2903 - 30164352.41
putative type iii restriction enzyme r proteinHPHPA16_0006P44105+3262 - 559891288.5
adenine-specific dna-methyltransferaseHPHPA16_0007Not Available+5592 - 746671875.1
putative endonuclease gHPHPA16_0008Not Available+7583 - 844633487.5
hypothetical proteinHPHPA16_0009Not Available-8679 - 88014310.34
prephenate dehydrogenaseHPHPA16_0010P20692-8879 - 970630575.5

Displaying genes 1 – 10 of 1703 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 93 metabolites