Helicobacter pylori Hp H-44

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp H-44 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and arrangement in singles. This organism is typically associated with host environments, thriving optimally at a temperature of 37.0°C, which aligns with the human body temperature, suggesting its adaptation to a specific biological niche. H. pylori is known for its ability to colonize the gastric mucosa of the stomach, where it may play a role in various gastrointestinal conditions. The microaerophilic nature of H. pylori indicates that it requires low levels of oxygen for growth, which is consistent with its gastric habitat, where oxygen levels are reduced compared to atmospheric conditions. The combination of its unique morphology, temperature preference, and oxygen requirement highlights its specialization for survival in the human stomach, an environment that presents both challenges and opportunities for microbial colonization. Understanding the traits of H. pylori Hp H-44 can provide valuable insights into its ecological role within the human microbiome and its potential interactions with host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp H-44

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp H-44
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp H-44


Gene Summary

Adenine Count

503896 bp

Thymine Count

510338 bp

Guanine Count

323785 bp

Cytosine Count

327821 bp

Genome Length

1665840 bp

Protein-coding Genes

1661 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
putative membrane proteinHPHPH44_0001Not Available+1 - 2208966.34
5s ribosomal rnaNot AvailableNot Available+20 - 135Not Available
5s ribosomal rnaNot AvailableNot Available+127 - 242Not Available
yihy family proteinHPHPH44_0002Not Available-464 - 134234609.7
biotin synthaseHPHPH44_0003Q1CRM5-1342 - 219031457.8
hypothetical proteinHPHPH44_0004Not Available+2317 - 24484937.12
putative type iii restriction enzyme r proteinHPHPH44_0005P44105+2604 - 496492194.9
methyltransferaseHPHPH44_0006P71366+4958 - 690175323.0
16s ribosomal rnaNot AvailableNot Available+6135 - 7623Not Available
putative endonuclease gHPHPH44_0007Not Available+7024 - 788733567.5

Displaying genes 1 – 10 of 1702 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 93 metabolites