Helicobacter pylori Hp A-9

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp A-9 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe is notably microaerophilic, thriving in environments with reduced oxygen levels, which aligns with its habitat as a host-associated organism. The optimal growth temperature for H. pylori Hp A-9 is approximately 37.0°C, reflecting its adaptation to the warm conditions typically found in the gastrointestinal tracts of various hosts, including humans. H. pylori is known for its unique ability to colonize the gastric mucosa, and its morphology, particularly the helical structure, is thought to facilitate motility in viscous environments such as mucus. The microaerophilic nature of H. pylori Hp A-9 suggests that it may have evolved specific metabolic pathways to survive in low-oxygen niches, potentially influencing its interactions with the host's immune system and other microbial inhabitants of the gastrointestinal ecosystem. Understanding the specific traits and adaptations of H. pylori Hp A-9 can provide insight into its role in the complex microbiome of the stomach, where it may engage in intricate relationships with both the host and other microbial species. This highlights the importance of studying strain-specific characteristics to unravel the ecological dynamics within the gastric environment.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp A-9

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp A-9
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp A-9


Gene Summary

Adenine Count

519991 bp

Thymine Count

534023 bp

Guanine Count

330631 bp

Cytosine Count

335762 bp

Genome Length

1720407 bp

Protein-coding Genes

1754 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
chaperonin grolHPHPA9_0050Q1CVE5Negative33014 - 3465458245.5
10 kda chaperoninHPHPA9_0051B5Z6D2Negative34680 - 3503612989.7
dna primaseHPHPA9_0052Q9ZN49Positive35324 - 3700363353.5
trna (5-methylaminomethyl-2-thiouridylate)-methyltransferaseHPHPA9_0053Not AvailablePositive37000 - 3805240021.6
valyl-trna synthetaseHPHPA9_0054Not AvailablePositive38142 - 3896931876.0
comb2 competence proteinHPHPA9_0055Not AvailablePositive39115 - 3939610540.4
comb3 competence proteinHPHPA9_0056Not AvailablePositive39396 - 3965910034.7
comb4 competence proteinHPHPA9_0057Not AvailablePositive39661 - 4202490200.7
hypothetical proteinHPHPA9_0058Not AvailablePositive42327 - 4366750953.6
chemotaxis proteinHPHPA9_0059O24864Positive43775 - 4474036562.2

Displaying genes 51 – 60 of 1797 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 93 metabolites

Health Effects

No health effects information available for this bacterium.