Helicobacter pylori NQ4161

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori NQ4161 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. It possesses flagella, which contribute to its mobility, although it is classified as non-motile in terms of movement through environments. The organism is adapted to a host-associated habitat, indicating a close relationship with its living host. This bacterium thrives optimally at 37 degrees Celsius, reflecting its mesophilic nature, which is typical for many pathogens that inhabit warm-blooded hosts. H. pylori NQ4161 is notable for having a single replicon and a double membrane structure, aligning with the structural characteristics of many Gram-negative bacteria. As a free-living organism, H. pylori NQ4161 contributes to its ecological niche, particularly in the human stomach where it can survive in a microaerophilic environment. The ability to thrive in such conditions suggests a specialized adaptation to the gastric microenvironment, which has implications for its role in gastrointestinal health and disease. The presence of this bacterium is often associated with gastric inflammation and ulcers, underscoring its significance in human health. Overall, the unique traits of H. pylori NQ4161 highlight its role in microbial ecology and its potential impact on host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNQ4161

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori NQ4161
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori NQ4161


Gene Summary

Adenine Count

498810 bp

Thymine Count

503311 bp

Guanine Count

318473 bp

Cytosine Count

322623 bp

Genome Length

1643218 bp

Protein-coding Genes

1678 genes

Non-Coding Genes

44 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
response regulatorHPNQ4161_0459O25408Positive447353 - 44849843394.8
excinuclease abc subunit aHPNQ4161_0460Q9ZLD6Negative449168 - 451993104789.0
outer membrane proteinHPNQ4161_0461Not AvailablePositive452167 - 45297929601.0
5s ribosomal rnaNot AvailableNot AvailablePositive452194 - 452307Not Available
23s ribosomal rnaNot AvailableNot AvailablePositive452548 - 455433Not Available
hypothetical proteinHPNQ4161_0462Not AvailableNegative453054 - 4531764687.69
s-adenosyl-methyltransferase mrawHPNQ4161_0463Q9ZLD4Positive453153 - 45407934782.2
hypothetical proteinHPNQ4161_0464Not AvailablePositive454100 - 45444413312.0
hypothetical proteinHPNQ4161_0465Not AvailablePositive454444 - 4546236738.54
acetolactate synthase 3 regulatory subunitHPNQ4161_0466O58212Positive454896 - 45579833086.8

Displaying genes 461 – 470 of 1722 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites

Health Effects

No health effects information available for this bacterium.