Roseburia sp.

Gram-positiveNon-motile

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Roseburia

Description

Roseburia sp. is a nonsporulating, mesophilic bacterium known for its fermentative metabolism and role as a chemoheterotroph. This microbe is primarily found in the intestinal microflora of animals, including humans, where it plays a crucial role in gut health and metabolism. As a member of the human gut microbiota, Roseburia sp. contributes to the fermentation of dietary fibers, producing short-chain fatty acids (SCFAs) such as butyrate, which is vital for colon health and has various beneficial effects on host metabolism. Roseburia species are particularly significant for their association with dietary habits and overall gut microbiome composition. Their abundance has been inversely correlated with several metabolic disorders and inflammatory conditions. Studies suggest that a higher prevalence of Roseburia sp. can be linked to a fiber-rich diet, highlighting the importance of dietary intake in shaping gut microbial communities. Additionally, Roseburia sp. has garnered attention due to its potential therapeutic role in managing conditions like obesity and inflammatory bowel diseases. By modulating the gut microbiota and enhancing butyrate production, this bacterium may help in reducing inflammation and improving metabolic profiles in hosts. In summary, Roseburia sp. exemplifies the intricate interplay between diet, gut microbiota, and host health, emphasizing the importance of maintaining a diverse and balanced microbial community for overall well-being. Its ability to generate energy from fermentation processes and produce beneficial SCFAs reinforces its ecological significance within the gut ecosystem.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusRoseburia
SpeciesRoseburia sp.
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal Intestinal Microflora
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Roseburia sp.


Gene Summary

Adenine Count

759244 bp

Thymine Count

773148 bp

Guanine Count

730861 bp

Cytosine Count

765134 bp

Genome Length

3047017 bp

Protein-coding Genes

2675 genes

Non-Coding Genes

38 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
ribosomal-protein-alanine n-acetyltransferaseDF667_00050Not Available+8566 - 900316033.4
Ncrna_class:rnase_p_rnaNot AvailableNot Available+9018 - 9389Not Available
hypothetical proteinDF667_00055Not Available+9117 - 93629249.99
ribonuclease zDF667_00060Not Available+9381 - 1029834246.7
hypothetical proteinDF667_00065Not Available+10319 - 1090322638.3
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex transferase subunit tsadDF667_00070Not Available+10893 - 1191836242.7
2-c-methyl-d-erythritol 4-phosphate cytidylyltransferaseDF667_00075Not Available+11918 - 1262225776.1
l-serine ammonia-lyase, iron-sulfur-dependent, subunit alphaDF667_00080Not Available-13018 - 1389030344.7
l-serine ammonia-lyase, iron-sulfur-dependent, subunit betaDF667_00085Not Available-13980 - 1464523643.7
csor family transcriptional regulatorDF667_00090Not Available+14823 - 1527516443.1

Displaying genes 11 – 20 of 5423 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites