Bifidobacterium breve HPH0326

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve HPH0326 is a gram-positive, rod-shaped bacterium classified as a mesophile, thriving optimally at moderate temperatures, and is a heterotrophic organism, deriving its energy from complex organic compounds. This microbe is identified primarily in the gastrointestinal tracts of humans and various mammals, particularly in the intestines of infants and young children, and can also be found in other body sites such as the oral cavity and occasionally in the urogenital tract. As a member of the Bifidobacterium genus, B. breve HPH0326 is an obligate anaerobe, meaning it cannot survive in the presence of oxygen and instead flourishes in low-oxygen environments typical of the gut. This characteristic is pivotal for its ecological niche, where it plays a crucial role in the maintenance of gut health by promoting a balanced microbiota and aiding in digestion. The heterotrophic nature of B. breve HPH0326 enables it to utilize various carbohydrates, including dietary fibers and oligosaccharides, which it ferments to produce short-chain fatty acids (SCFAs). These SCFAs serve essential functions, including providing energy to colonic cells, enhancing gut barrier integrity, and exhibiting anti-inflammatory properties. Furthermore, Bifidobacterium breve HPH0326 has garnered attention for its potential probiotic benefits, including the modulation of gut microbiota composition and the relief of gastrointestinal disorders. Its ability to produce antimicrobial substances adds to its protective role against pathogenic bacteria, offering a natural method to improve intestinal health. Current research is exploring its therapeutic applications in areas like immune modulation and the prevention of allergic conditions, highlighting its significance in both health and disease management.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainHPH0326

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve HPH0326


Gene Summary

Adenine Count

515139 bp

Thymine Count

508418 bp

Guanine Count

739726 bp

Cytosine Count

739274 bp

Genome Length

2502557 bp

Protein-coding Genes

2090 genes

Non-Coding Genes

111 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+450032 - 450044Not Available
Hnh endonucleaseHMPREF1482_00386Not Available+464286 - 46464213532.9
Hypothetical proteinHMPREF1482_00387Not Available+464730 - 46502010508.2
TerminaseHMPREF1482_00388Not Available+465004 - 46643753267.7
Portal proteinHMPREF1482_00389Not Available+466437 - 46793655485.2
Capsid maturation proteaseHMPREF1482_00390Not Available+467887 - 46908945399.3
hypothetical proteinHMPREF1482_00391Not Available+469047 - 4693079670.15
Gp10HMPREF1482_00392Not Available+469439 - 46997219247.4
Major capsid proteinHMPREF1482_00393Not Available+470018 - 47092332731.1
Putative head fiber proteinHMPREF1482_00394Not Available+470923 - 47123710393.5

Displaying genes 1 – 10 of 2201 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

134 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm0002143menaquinone-7C46H64O2Chemical structure of menaquinone-7Not available
Average648.9992Da
Monoisotopic648.4906313Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0003070D-methionineC5H11NO2SChemical structure of D-methionine348-67-4
Average149.211Da
Monoisotopic149.0510493Da
BASm0003462(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinateC13H19N4O12PChemical structure of (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate3031-95-6
Average454.2833Da
Monoisotopic454.0737086Da
BASm0003971heme bC34H30FeN4O4Not available14875-96-8
Average614.484Da
Monoisotopic614.162739Da

Displaying 1–10 of 134 metabolites