Helicobacter pylori Hp P-8

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp P-8 is a Gram-negative bacterium characterized by its spiral shape and solitary cell arrangement. This microbe is microaerophilic, thriving in environments with reduced oxygen levels, which aligns with its typical habitat associated with the host. Optimal growth occurs at 37.0°C, a temperature that corresponds with the physiological conditions of the human gastric environment, where H. pylori is predominantly found. As a member of the Helicobacter genus, Hp P-8’s morphological traits and growth requirements suggest an adaptation to the acidic and low-oxygen conditions of the stomach. Its spiral shape may facilitate motility, allowing it to navigate the viscous mucus layer that protects the gastric epithelium. This unique morphology, combined with its microaerophilic nature, likely plays a critical role in its survival and potential interactions within the gastric niche. Understanding the traits of Helicobacter pylori Hp P-8 enhances our insight into the functional dynamics of gastric microbiota, particularly in relation to host-microbe interactions. The specific adaptations of this strain may contribute to its ecological role in the gastric environment, influencing both microbial community structure and host health. Further research into these relationships could reveal important implications for gastrointestinal health and disease management.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp P-8

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp P-8
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp P-8


Gene Summary

Adenine Count

489051 bp

Thymine Count

492584 bp

Guanine Count

316577 bp

Cytosine Count

317414 bp

Genome Length

1615626 bp

Protein-coding Genes

1628 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+669 - 784Not Available
hypothetical proteinHPHPP8_0002Not Available+791 - 9616975.73
yihy family proteinHPHPP8_0003Not Available-1017 - 189534571.0
biotin synthaseHPHPP8_0004O25956-1895 - 274331476.8
putative type iii restriction endonucleaseHPHPP8_0005P44105+3151 - 549091295.5
methyltransferaseHPHPP8_0006P71366+5484 - 741574424.6
putative endonuclease gHPHPP8_0007Not Available+7540 - 840333614.8
prephenate dehydrogenaseHPHPP8_0008P20692-8845 - 967230415.3
atp-dependent protease laHPHPP8_0009Q9ZJL3-9681 - 1217093690.3
competence lipoproteinHPHPP8_0010O25930-12213 - 1287526197.7

Displaying genes 1 – 10 of 1669 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites